Cost containment analysis of superparamagnetic iron oxide (SPIO) injection in patients with ductal carcinoma in situ.

IF 3 3区 医学 Q2 ONCOLOGY
Breast Cancer Research and Treatment Pub Date : 2024-12-01 Epub Date: 2024-08-01 DOI:10.1007/s10549-024-07451-2
Odette Solís, Jamin Addae, Raeshell Sweeting, Ingrid Meszoely, Ana Grau, Rondi Kauffmann, Mark Kelley, Rachel McCaffrey, Kelly Hewitt
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引用次数: 0

Abstract

Purpose: Recent studies have established the safety and efficacy of Superparamagnetic Iron Oxide (SPIO, Magtrace®) for delayed sentinel lymph node biopsy (SLNB) in patients with ductal carcinoma in situ (DCIS) who are undergoing mastectomy. The aim of our study was to measure cost containment with use of Magtrace® in comparison to upfront SLNB with traditional technetium-99 lymphatic tracer.

Methods: A total of 41 patients at our institution underwent mastectomy with Magtrace® injection for DCIS and were included in our single-institution, retrospective analysis. For comparison, total charges data were obtained for an upfront SLNB at the time of mastectomy. Cost comparison analysis was then performed against charges for intraoperative Magtrace® injection with additional charges incorporated for those patients who required return to the operating room for delayed SLNB. Total cost containment for the cohort with use of Magtrace® was then measured.

Results: Of the 41 patients who underwent Magtrace® injection, two patients required return to the operating room for a delayed SLNB for invasive disease. Including these charges for a second encounter into our cost analysis, the use of Magtrace® still yielded an overall cost containment of $205,793.55 in our cohort when comparing to patients who underwent upfront SLNB. For patients who underwent Magtrace® injection and did not require return to the operating room, charges were reduced by $6,768.52 per patient.

Conclusion: The use of Magtrace® for delayed SLNB in patients with DCIS undergoing mastectomy yielded a significant overall cost containment, further supporting its use in this patient population.

导管原位癌患者注射超顺磁性氧化铁 (SPIO) 的成本控制分析。
研究目的最近的研究证实了超顺磁性氧化铁(SPIO,Magtrace®)对接受乳房切除术的乳腺导管原位癌(DCIS)患者进行延迟前哨淋巴结活检(SLNB)的安全性和有效性。我们的研究旨在衡量使用 Magtrace® 与使用传统锝-99 淋巴示踪剂进行前期 SLNB 的成本控制情况:方法:我院共有 41 名患者接受了注射 Magtrace® 治疗 DCIS 的乳房切除术,并纳入了我们的单机构回顾性分析。为了进行比较,我们还获得了在乳房切除术时进行前期 SLNB 的总费用数据。然后根据术中注射 Magtrace® 的费用进行成本比较分析,并对需要返回手术室进行延迟 SLNB 的患者收取额外费用。然后对使用 Magtrace® 的患者群的总成本控制情况进行了测算:结果:在接受 Magtrace® 注射的 41 名患者中,有两名患者因浸润性疾病需要返回手术室进行延迟 SLNB。将这些二次就诊的费用纳入成本分析后,与接受前期 SLNB 的患者相比,使用 Magtrace® 仍为我们的队列节省了 205,793.55 美元的总成本。对于接受 Magtrace® 注射且无需返回手术室的患者,每位患者的费用减少了 6,768.52 美元:结论:在接受乳房切除术的 DCIS 患者中使用 Magtrace® 进行延迟 SLNB 可显著降低总体成本,进一步支持在此类患者中使用 Magtrace®。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.80
自引率
2.60%
发文量
342
审稿时长
1 months
期刊介绍: Breast Cancer Research and Treatment provides the surgeon, radiotherapist, medical oncologist, endocrinologist, epidemiologist, immunologist or cell biologist investigating problems in breast cancer a single forum for communication. The journal creates a "market place" for breast cancer topics which cuts across all the usual lines of disciplines, providing a site for presenting pertinent investigations, and for discussing critical questions relevant to the entire field. It seeks to develop a new focus and new perspectives for all those concerned with breast cancer.
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