Ferritin Levels among Hypertensive Disorders of Pregnancy in a Tertiary Care Hospital Setting: A Pilot Study

Q4 Medicine
Mukul Sharma, Vedant Shekhar Jha, K. Bhatia, Pratibha Misra, Bhasker Mukherjee, Bidhan Roy
{"title":"Ferritin Levels among Hypertensive Disorders of Pregnancy in a Tertiary Care Hospital Setting: A Pilot Study","authors":"Mukul Sharma, Vedant Shekhar Jha, K. Bhatia, Pratibha Misra, Bhasker Mukherjee, Bidhan Roy","doi":"10.4103/mjdrdypu.mjdrdypu_614_23","DOIUrl":null,"url":null,"abstract":"ABSTRACT\n \n \n \n According to a WHO report, the prevalence of anemia is the highest in children less than five years of age (40%) and pregnant women of the global population (37%). The prevalence of hypertensive disorders of pregnancy was 7.8% in India. 14% of maternal deaths are attributed to hypertensive disorders of pregnancy, according to a WHO report. Our study aimed to evaluate the variation of serum ferritin (SF) levels in four different groups: (1) normal pregnancy, (2) pregnancy with anemia, (3) pregnancy with hypertensive disorders, and (4) pregnancy with hypertensive disorders and anemia, to derive an association of SF in patients of anemia and hypertensive disorders of pregnancy.\n \n \n \n Thirty diagnosed cases of each predefined group of similar gestation were enrolled. A venous blood sample was collected from all subjects of all four groups for estimation of SF levels and hemoglobin levels.\n \n \n \n SF level was found to be significantly around twofold higher in groups 3 and 4 with hypertensive disorders of pregnancy (60.6 ± 27.5 μg/dL and 54.4 ± 26 μg/dL, respectively) compared to normal pregnancy and pregnancy with anemia (31.3 ± 25 μg/dL and 23.3 ± 21.6 μg/dL, respectively). Hence, the Kruskal–Wallis test was conducted for four groups, and it was statistically significant.\n \n \n \n In our study, pregnant women with anemia had lower SF levels than normal pregnancy cases. However, in group 4 with hypertensive disorders of pregnancy with anemia SF levels were higher than group 2.\n","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_614_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

ABSTRACT According to a WHO report, the prevalence of anemia is the highest in children less than five years of age (40%) and pregnant women of the global population (37%). The prevalence of hypertensive disorders of pregnancy was 7.8% in India. 14% of maternal deaths are attributed to hypertensive disorders of pregnancy, according to a WHO report. Our study aimed to evaluate the variation of serum ferritin (SF) levels in four different groups: (1) normal pregnancy, (2) pregnancy with anemia, (3) pregnancy with hypertensive disorders, and (4) pregnancy with hypertensive disorders and anemia, to derive an association of SF in patients of anemia and hypertensive disorders of pregnancy. Thirty diagnosed cases of each predefined group of similar gestation were enrolled. A venous blood sample was collected from all subjects of all four groups for estimation of SF levels and hemoglobin levels. SF level was found to be significantly around twofold higher in groups 3 and 4 with hypertensive disorders of pregnancy (60.6 ± 27.5 μg/dL and 54.4 ± 26 μg/dL, respectively) compared to normal pregnancy and pregnancy with anemia (31.3 ± 25 μg/dL and 23.3 ± 21.6 μg/dL, respectively). Hence, the Kruskal–Wallis test was conducted for four groups, and it was statistically significant. In our study, pregnant women with anemia had lower SF levels than normal pregnancy cases. However, in group 4 with hypertensive disorders of pregnancy with anemia SF levels were higher than group 2.
一家三级医院妊娠期高血压疾病患者的铁蛋白水平:一项试点研究
ABSTRACT 根据世界卫生组织的一份报告,在全球人口中,五岁以下儿童(40%)和孕妇(37%)的贫血患病率最高。在印度,妊娠高血压疾病的发病率为 7.8%。世卫组织的一份报告显示,14% 的孕产妇死亡归因于妊娠高血压疾病。我们的研究旨在评估四个不同组别的血清铁蛋白(SF)水平变化:(1) 正常妊娠;(2) 贫血妊娠;(3) 妊娠合并高血压疾病;(4) 妊娠合并高血压疾病和贫血。 每个预定组别均有 30 名妊娠期相近的确诊病例。从所有四组受试者身上采集静脉血样本,以估算 SF 水平和血红蛋白水平。 结果发现,与正常妊娠和贫血妊娠(分别为 31.3 ± 25 μg/dL 和 23.3 ± 21.6 μg/dL)相比,患有妊娠高血压疾病的第 3 组和第 4 组的 SF 水平(分别为 60.6 ± 27.5 μg/dL 和 54.4 ± 26 μg/dL)明显高出两倍左右。因此,对四个组别进行了 Kruskal-Wallis 检验,结果具有统计学意义。 在我们的研究中,贫血孕妇的 SF 水平低于正常孕妇。然而,在患有妊娠高血压疾病并伴有贫血的第 4 组中,SF 水平高于第 2 组。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
0.30
自引率
0.00%
发文量
221
审稿时长
43 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信