{"title":"Perioperative management of patients with postoperative nausea and vomiting (PONV) risks","authors":"Jonathan Pang, Alfred Chan","doi":"10.1016/j.mpaic.2024.07.011","DOIUrl":null,"url":null,"abstract":"<div><p>Postoperative nausea and vomiting (PONV) is a common distressing symptom for patients undergoing surgery and anaesthesia, with incidence ranging from 30% in the general population up to 80% in the high-risk cohort. PONV increases patient dissatisfaction, with additional surgical and anaesthetic implications such as aspiration, wound dehiscence and raised intracranial pressure</p><p>This article highlights multifactorial aetiologies of PONV including patient, anaesthetic and surgical related factors. Neuropharmacology including activation of various receptors (dopaminergic, muscarinic, serotonergic) and cranial nerves VIII (acoustic-vestibular), IX (glossopharyngeal) and X (vagus nerve) is discussed. The most up-to-date PONV management and novel therapies are also discussed after literature review.</p></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"25 8","pages":"Pages 555-559"},"PeriodicalIF":0.2000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029924001528","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
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Abstract
Postoperative nausea and vomiting (PONV) is a common distressing symptom for patients undergoing surgery and anaesthesia, with incidence ranging from 30% in the general population up to 80% in the high-risk cohort. PONV increases patient dissatisfaction, with additional surgical and anaesthetic implications such as aspiration, wound dehiscence and raised intracranial pressure
This article highlights multifactorial aetiologies of PONV including patient, anaesthetic and surgical related factors. Neuropharmacology including activation of various receptors (dopaminergic, muscarinic, serotonergic) and cranial nerves VIII (acoustic-vestibular), IX (glossopharyngeal) and X (vagus nerve) is discussed. The most up-to-date PONV management and novel therapies are also discussed after literature review.
期刊介绍：
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.
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