The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy

Abstract

Background: Oral mucositis (OM) is a common complication in cancer patients receiving radiotherapy or chemotherapy, impacting treatment outcome. Prevention and treatment of OM is an urgent problem in the field of anticancer therapy. This study aimed to evaluate the efficacy of honey with or without propolis in prevention and treatment of OM. Patients and methods : This study was conducted at the Oncology Center, Mansoura University. Eighty patients were included and were classified into three groups: First group consisted of 30 patients, received pure natural commercial honey (40 ml divided into 4 times daily); Second group (30 patients), received same amount of honey in addition to propolis (0.5gram) and the third group (control group