Acute methanol poisoning

R. A. Narzikulov, A. H. Lodyagin, B. V. Batotsyrenov, O. Kuznetsov
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Abstract

According to the state report «On the state of sanitary and epidemiological welfare of the population in the Russian Federation in 2021», the indicator of acute poisoning with alcohol- containing products amounted to 21.19 cases per 100 thousand population [1]. The purpose of the study: analytical toxicological analysis, features of diagnosis and intensive care of patients hospitalized with acute methanol poisoning in the toxicological center of the metropolis. Materials and methods of research. The medical documents of 46 patients admitted to the Acute Poisoning Center were analyzed GBU St. Petersburg Research Institute of Joint Venture named after I. I. Janelidze in 2019–2022 with a diagnosis of «Acute methanol poisoning». Category ICD-10: T51.1. A statistical and chemical- toxicological study was conducted upon admission of patients to the hospital and in dynamics after intensive care. The results of the study. According to the data of the Central Research Center of the St. Petersburg Research Institute of Joint Venture named after I. I. Janelidze, the number of patients with acute methyl alcohol poisoning was: 2019, 10 patients were admitted (of which 3 patients died); 2020, 11 patients (3 died); 2021, 12 patients out of 15 patients died; 2022, out of 10 patients with acute poisoning 7 patients died with methanol. All admitted patients with acute methyl alcohol poisoning were in critical condition with severe disorders of vital organs. Conclusion: methanol poisoning occupies one of the leading places among acute poisoning of chemical etiology both in frequency and in the number of adverse outcomes. They are characterized by severe medical, social and economic consequences.
急性甲醇中毒
根据《2021 年俄罗斯联邦居民卫生和流行病福利状况》国家报告,每 10 万人口中酒精产品急性中毒指标为 21.19 例[1]。本研究的目的是:对大都会毒物学中心住院的急性甲醇中毒患者进行毒物学分析、诊断特点和重症监护。研究材料和方法。以 I. I. Janelidze 命名的 GBU 圣彼得堡联合企业研究所对急性中毒中心收治的 46 名患者的医疗文件进行了分析。Janelidze 命名的合资企业研究院)2019-2022 年诊断为 "急性甲醇中毒 "的 46 名患者的医疗文件进行了分析。类别 ICD-10:T51.1。对患者入院时和重症监护后的动态情况进行了统计和化学毒理学研究。研究结果根据以 I. I. Janelidze 命名的圣彼得堡合资企业研究所中央研究中心的数据,入院病人的数量和入院后的动态变化均呈上升趋势。Janelidze 命名的联合企业研究所中央研究中心的数据,急性甲醇中毒患者的人数为:2019 年,收治 10 名患者(其中 3 名患者死亡);2020 年,收治 11 名患者(3 名患者死亡);2021 年,15 名患者中有 12 名患者死亡;2022 年,10 名急性中毒患者中有 7 名甲醇中毒患者死亡。所有入院的急性甲醇中毒患者均病情危重,重要器官功能严重紊乱。结论:甲醇中毒无论在发生频率还是不良后果的数量上,都在化学病因急性中毒中占据领先地位。其特点是造成严重的医疗、社会和经济后果。
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