Clinical application of "Ethoxysclerol" and "Bleomycin" in the management of retention cysts of the salivary glands in pediatric patients: case studies

T. Bakshi, S. Yakovlev, O. Topol’nitskiy, A. P. Gurgenadze
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Abstract

Relevance. Retention cysts of the salivary glands are a frequent occurrence in dental practice. Traditional treatments, such as cystadenectomy and cystotomy, are commonly employed. However, these procedures are associated with postoperative complications, including recurrence, damage to adjacent structures (e.g., ducts of neighbouring salivary glands, blood vessels, and nerves), and inadvertent opening of the submandibular salivary gland capsule.Description of clinical cases. This paper presents clinical cases of four pediatric patients diagnosed with retention cysts of the salivary glands, treated at the Department of Pediatric Maxillofacial Surgery, Russian University of Medicine. All patients received treatment with "Lauromacrogol-400" ("Ethoxysclerol") and "Bleomycin." In the postoperative period, no complications or adverse effects related to the administered drugs were observed. Follow-up examinations revealed no clinical manifestations of retention cysts or ultrasonographic evidence of cysts.Conclusions. Sclerotherapy using "Ethoxysclerol" and "Bleomycin" for the treatment of retention cysts of the salivary glands presents a viable minimally invasive alternative to conventional surgical methods, potentially mitigating the risks associated with more invasive procedures.
乙氧基硬化剂 "和 "博莱霉素 "在治疗儿童唾液腺潴留囊肿中的临床应用:病例研究
相关性。唾液腺潴留囊肿是牙科临床中的常见病。通常采用囊肿切除术和囊肿切开术等传统治疗方法。然而,这些手术都与术后并发症有关,包括复发、损伤邻近结构(如邻近唾液腺的导管、血管和神经)以及不慎打开颌下腺唾液腺囊。本文介绍了在俄罗斯医科大学小儿颌面外科系接受治疗的四名被诊断为唾液腺潴留囊肿的小儿患者的临床病例。所有患者均接受了 "Lauromacrogol-400"("Ethoxysclerol")和 "Bleomycin "治疗。术后未发现与用药有关的并发症或不良反应。随访检查未发现潴留囊肿的临床表现或超声波检查证据。使用 "乙氧基硬化剂 "和 "博莱霉素 "进行硬化剂注射治疗唾液腺潴留囊肿是传统手术方法的一种可行的微创替代方法,有可能降低与更具创伤性的手术相关的风险。
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