A Surgical management of Mandibular Central Giant Cell Granuloma: A case report

Abstract

Central giant cell granuloma (CGCG) is a benign intraosseous, it is a nonneoplastic lesion that is found particularly in the maxilla and mandible, with higher rate in the mandible. Although the etiology is uncertain, it is assumed to be caused by trauma, inflammatory processes, or genetic factors. The biologic behavior of CGCG of the jaws ranges from a quiescent, indolent asymptomatic lesion with slow growth and low recurrence rate, to an aggressive pathological process, characterized by pain, rapid growth, root resorption, cortical perforation, and a high recurrence rate. A rapid diagnostic assessment, together with an adequate histopathologic verification, is essential to improve the management and the prognosis of this locally destructive lesion. In this case report, a 63-year-old female patient complaining of a lower left side mandibular swelling measured (3x3cm) for two months undergone radiographic investigation. Images revealed a mandibular left side lesion with characteristic features that were highly suggestive of CGCG. The patient undergone excisional biopsy, and the subsequent histopathological examination confirmed the diagnosis of CGCG. Postoperative recovery of the patient was smooth and uneventful. The mild postoperative pain and edema were controlled with analgesic anti-inflammatory drugs, and the patient was placed on intravenous broad-spectrum antibiotics for 5 days, The surgery and recovery were uneventful.