Analysis of Radiation Dose Rate and Evaluation of Whole Body Scan SPECT/CT Images in Thyroid Carcinoma Radioablation Patients Using Radioisotope 131I

Indah Maulidina, Zaenal Arifin, Zaenul Muhlisin, M. Roeslan Abdul Gani, Junan Imaniar Pribadi
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Abstract

The incidence rate of thyroid carcinoma shows an increasing trend from year to year. One method for treating thyroid carcinoma is radioablation therapy using 131I. The use of 131I must be carried out in accordance with radiation safety regulations to avoid undesirable radiation dose rates. Therefore, research was conducted to analyze the radiation dose rate emitted by patients, obtain the relationship between body mass index (BMI) and the emitted dose rate, and evaluate whole body scan images of Single-Photon Emission Computed Tomography (SPECT/CT) of thyroid carcinoma radioablation patients. The research was carried out by measuring the patient's radiation dose rate using a surveymeter. The sample used was 53 patients who met the inclusion criteria and were not included in the exclusion criteria. The patient is isolated until it is safe to leave the hospital, then the therapy is evaluated by means of a whole body scan using SPECT/CT. Region of Interest (ROI) was carried out on the thyroid, stomach, liver, large intestine and bladder. On the third day the patient's dose rate value was below 70 μSv/h so that the patient could go home safely in accordance with radiation protection regulations. The average dose rate value for obese patients was higher compared to patients with low, normal and excess BMI. The high organ radiation count value for whole body SPECT/CT scan patients is caused by several factors such as the absorption of 131I by organs and the buildup of radioisotopes in organs.
使用放射性同位素 131I 对甲状腺癌放射性消融患者进行辐射剂量率分析和全身扫描 SPECT/CT 图像评估
甲状腺癌的发病率呈逐年上升趋势。治疗甲状腺癌的方法之一是使用 131I 进行放射性消融治疗。131I 的使用必须符合辐射安全法规,以避免不良辐射剂量率。因此,研究人员分析了患者的辐射剂量率,获得了身体质量指数(BMI)与辐射剂量率之间的关系,并对甲状腺癌放射消融患者的单光子发射计算机断层扫描(SPECT/CT)全身扫描图像进行了评估。研究是通过测量仪测量患者的辐射剂量率进行的。所用样本为 53 名符合纳入标准且未被纳入排除标准的患者。患者被隔离直至可以安全离开医院,然后通过 SPECT/CT 全身扫描对治疗进行评估。对甲状腺、胃、肝、大肠和膀胱进行感兴趣区(ROI)扫描。第三天,患者的剂量率值低于 70 μSv/h,因此患者可以按照辐射防护规定安全回家。与低体重指数、正常体重指数和超重体重指数患者相比,肥胖患者的平均剂量率值更高。全身 SPECT/CT 扫描患者的器官辐射计数值较高是由多个因素造成的,如器官对 131I 的吸收和放射性同位素在器官中的积聚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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