Pediatric Case: Serum Protein Electrophoretic

Abstract

Serum protein electrophoresis is a straightforward, dependable and precise technique employed to separate serum proteins. This research aimed to discover abnormal patterns of serum proteins in pediatric cases using capillary electrophoresis and to interpret any detected abnormalities. The research involved 92 serum samples obtained from pediatric patients admitted to Children’s Hospital in Casablanca. The study findings identified distinctive pathological electrophoretic patterns observed in pediatric cases: 36 children showed patterns indicative of inflammatory response, 3 had nephrotic syndrome, 4 had hypogammaglobulinemia, 24 exhibited polyclonal hypergammaglobulinemia and 1 had hypoproteinemia. Additionally, two rare cases of α1-antitrypsin deficiency were highlighted through electrophoresis. Serum protein electrophoresis is highly recommended as a diagnostic tool in children to enhance the accuracy of diagnosing inflammatory diseases, liver disorders and immunodeficiency cases.