Erythema Elevatum Diutinum in Association with IgA Monoclonal Gammopathy of Undetermined Significance

Katherine De Jong, Mojahed M. K. Shalabi, Dale Schaefer
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Abstract

Erythema Elevatum Diutinum (EED) is a distinctive form of chronic leukocytoclastic vasculitis characterized by red to brown papules, plaques, and nodules that favor the extensor aspect of the extremities. EED is a benign condition but may be associated with several systemic diseases, including hematologic disorders, infections, and autoimmune conditions. EED is a rare entity of vasculitis, with less than 400 cases being reported in world literature to date. We present a rare case of a 61-year-old male with IgA monoclonal gammopathy of undetermined significance (MGUS) and a 17-year history of EED that improved significantly with dapsone treatment. 
红斑隆起伴有意义不明的 IgA 单克隆丙种球蛋白病
肢端红斑(EED)是一种独特的慢性白细胞凝集性血管炎,其特征是四肢伸侧出现红色至棕色的丘疹、斑块和结节。EED 是一种良性疾病,但可能与多种全身性疾病相关,包括血液病、感染和自身免疫性疾病。EED 是一种罕见的血管炎,迄今为止全球文献报道的病例不到 400 例。我们报告了一例罕见病例,患者是一名61岁的男性,患有意义未定的IgA单克隆丙种球蛋白病(MGUS),并有17年的EED病史。
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