Prevalence of being ‘high-risk’ of hospitalization due to exacerbation among asthma patients aged ≥ 20 years in a district of Sri Lanka.

Dhanusha Punyadasa, V. Kumarapeli, Wijith Senaratne
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Abstract

Introduction: Hospitalizations due to exacerbated asthma remai ns high in Sri Lanka leaving a huge burden on the healthcare system. Identification of the burden of ‘high risk asthma  patients’ for hospitalization due to exacerbation is a cost-effective strategy for prioritizing management options. Objectives: To estimate the prevalence of ‘high-risk asthma patients ’ and selected risk predictors for hospitalization due to exacerbation among asthma patients aged ≥20 years in the district of  Gampaha, Sri Lanka Methods: A community-based descriptive cross-sectional study was  conducted among 1200 asthma patients aged ≥20 years, selected using a multistage sampling technique. The risk for hospi talization was assessed using a newly developed and validated risk prediction model. High-risk asthma patients were defi ned according to the cut-off value of the summary risk score of the model. Results: The prevalence of ‘high-risk asthma patients’ for hospitali zation due to exacerbation was 16.4% (95% CI: 14.2, 18.6). The prevalence of selected risk predictors: age ≥ 60 years 24.2%  (95% CI: 21.9, 26.7), poor educational attainment 67.3% (95% CI: 64.5, 70.0), having diabetes mellitus 18.8% (95%  CI: 16.5, 21.0), family history of asthma 41.3% (95% CI: 38.5, 44.2), ever smoked 12.2% (95% CI: 10.2, 14.1), ever int ubated or given intensive care 2.8% (95% CI: 1.8, 3.7), previous hospitalizations due to exacerbations 6.6% (95% CI: 5.1, 8.0) , having uncontrolled asthma 63.6% (95% CI: 60.8, 66.7), having symptomatic GORD 18% (95% CI: 15.7, 20.2) and ha ving body mass index (BMI) ≥ 25 kg/m2 36.3% (95% CI: 33.5, 39.0). Conclusions & Recommendations: A significant proportion of asthm a patients being at risk of hospitalization indicates the need to adopt cost-effective asthma management strategies to ac hieve better control of the disease. Prompt primary healthcare interventions are required to address modifiable risk predi ctors among asthma patients.
斯里兰卡某地区年龄≥ 20 岁的哮喘患者中因病情加重而住院的 "高危 "人群比例。
导言:在斯里兰卡,因哮喘恶化而住院治疗的人数居高不下,给医疗保健系统造成了巨大负担。确定 "高危哮喘患者 "因病情恶化而住院的负担是一项具有成本效益的策略,可优先考虑管理方案。目标:估算 "哮喘高危患者 "的患病率:估计斯里兰卡甘帕哈地区年龄≥20 岁的哮喘患者中 "高危哮喘患者 "的患病率以及因病情加重而住院的选定风险预测因素 方法:基于社区的描述性横断面调查:采用多阶段抽样技术,对 1200 名年龄≥20 岁的哮喘患者进行了社区描述性横断面研究。使用新开发并经过验证的风险预测模型评估了哮喘患者罹患癌症的风险。高危哮喘患者根据该模型的简要风险评分的临界值进行定义。结果显示因病情恶化住院的 "高危哮喘患者 "患病率为 16.4%(95% CI:14.2-18.6)。选定的风险预测因素包括:年龄≥ 60 岁 24.2% (95% CI: 21.9, 26.7)、受教育程度低 67.3% (95% CI: 64.5, 70.0)、患有糖尿病 18.8% (95% CI: 16.5, 21.0)、哮喘家族史 41.3% (95% CI: 38.5, 44.2)、吸烟 12.2% (95% CI: 10.2, 14.1)、吸烟或饮酒 14.2% (95% CI: 10.2, 14.1)、哮喘病史 41.3% (95% CI: 38.5, 44.2)。2.8%(95% CI:1.8,3.7),曾因病情加重住院 6.6%(95% CI:5.1,8.0),哮喘未得到控制 63.6%(95% CI:60.8,66.7),有症状的胃食管反流 18%(95% CI:15.7,20.2),体重指数(BMI)≥ 25 kg/m2 36.3%(95% CI:33.5,39.0)。结论与建议:相当一部分哮喘患者面临住院风险,这表明有必要采取具有成本效益的哮喘管理策略,以更好地控制病情。需要及时采取初级医疗保健干预措施,以应对哮喘患者中可改变的风险预测因素。
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