Verification of the insulin dosage method using Abbott Alinity ci®: experience of the biochemistry laboratory, CHU Mohammed IV Oujda, Morocco

Abstract

Introduction: The aim of our study was to evaluate the analytical performance of the insulin dosage method, which was performed by the Alinity ci® automated system in the biochemistry laboratory of the Mohammed VI University Hospital in Oujda. Insulin acts as an essential role in regulating the body's energy supply, mainly by balancing blood sugar levels via the storage of glucose in the liver, muscles and adipose tissue. Materials and methods: We carried out a study of the performance of the Alinity ci® automated system, assessing repeatability and reproducibility in accordance with the COFRAC GTA 04 accreditation technical guide, which meets the quality requirements of standard ISO 15 189. Results: The results of our study show satisfactory repeatability for the three levels (Low; Medium; High) with CV1 = 2.44 %, CV2 = 1.76 %, CV3 = 1.33 %. The reproducibility of insulin was also satisfactory, with respect to the coefficient of variation (CV) for the three levels (Low, Medium, High), respectively CV1 = 3.16 %, CV2 = 5.78 %, CV3 = 2.88 %. Conclusion: The reliability of our laboratory's insulin assay results is demonstrated by the satisfactory results obtained in our study, which comply with RICOS and FSCB recommendations.