Analysis of bioactive compounds present in Boerhavia elegans seeds by GC-MS

IF 2.1 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Open Chemistry Pub Date : 2024-07-25 DOI:10.1515/chem-2024-0068

Tahreer M. ALRaddadi, Saleh O. Bahaffi, Lateefa A. Alkhateeb, Mohammad W. Sadaka

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引用次数: 0

Abstract

Boerhavia elegans L. (Nyctaginaceae) is a tropical plant widely distributed in the eastern part of Yemen, Oman, and many other countries. B. elegans is used in traditional medicine to treat inflammation, anemia, and urinary tract disorders. The seeds, called Alhydawan, are used as food additives to prepare porridge, one of the most popular foods in Yemen. The present study aims to analyze the bioactive constituents of the methanolic extract of B. elegans seeds after fractionation on silica gel column chromatography. The methanolic extract was subjected to column chromatography and eluted with a hexane and hexane diethyl ether mixture of different compositions. The eluted fractions were tested with thin-layer chromatography. The gas chromatography-mass spectrometry analysis of fractions indicated some compounds such as dodecane, 2,6,11-trimethyl, butylated hydroxytoluene, 2,6,10-trimethyltridecane, hexadecane,2,6,11,15-tetramethyl, nonadecane, 2-methyl, 7,9-di-tert-butyl-1-oxaspiro(4,5) deca-6,9-diene-2,8-dione, n-hexadecenoic acid, octadecanoic acid, bis(2-ethylhexyl) phthalate, 13-docosenamide, (Z)-, and phenol,2,4-bis(1,1-dimethyl ethyl) phosphite (3:1). Hence, B. elegans may have antimicrobial, anticancer, antioxidant, and antidiabetic activities due to the presence of secondary metabolites in the extract.

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利用气相色谱-质谱法分析苧麻种子中的生物活性化合物

Boerhavia elegans L.（Nyctaginaceae）是一种热带植物，广泛分布于也门东部、阿曼和许多其他国家。在传统医学中，蛇麻草被用来治疗炎症、贫血和泌尿系统疾病。被称为 "Alhydawan "的种子被用作食品添加剂来制作粥，这是在也门最受欢迎的食物之一。本研究旨在分析经硅胶柱色谱分馏后的蚕豆种子甲醇提取物中的生物活性成分。甲醇提取物经柱层析，用不同成分的正己烷和正己烷二乙醚混合物洗脱。洗脱出的馏分用薄层色谱法进行检测。馏分的气相色谱-质谱分析表明了一些化合物，如十二烷、2,6,11-三甲基、丁基羟基甲苯、2,6,10-三甲基十三烷、十六烷、2,6,11,15-四甲基、壬烷、2-甲基、7,9-二叔丁基-1-氧杂螺(4,5)癸-6,9-二烯-2,8-二酮、正十六烯酸、十八酸、邻苯二甲酸二（2-乙基己基）酯、13-二十二烯酰胺 (Z)- 和苯酚、2,4-双（1,1-二甲基乙基）亚磷酸酯（3：1).因此，由于萃取物中存在次生代谢产物，秀丽草可能具有抗菌、抗癌、抗氧化和抗糖尿病活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

3.80

自引率

4.30%

发文量

审稿时长

6 weeks

期刊介绍： Open Chemistry is a peer-reviewed, open access journal that publishes original research, reviews and short communications in the fields of chemistry in an ongoing way. The central goal is to provide a hub for researchers working across all subjects to present their discoveries, and to be a forum for the discussion of the important issues in the field. The journal is the premier source for cutting edge research in fundamental chemistry and it provides high quality peer review services for its authors across the world. Moreover, it allows for libraries everywhere to avoid subscribing to multiple local publications, and to receive instead all the necessary chemistry research from a single source available to the entire scientific community.