Risk factors for postoperative acute pancreatitis after thoracic aortic surgery.

IF 0.7 Q3 Medicine

ASIAN CARDIOVASCULAR & THORACIC ANNALS Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI:10.1177/02184923241263919

Ryoma Ueda, Jiro Esaki, Hideki Tsubota, Masanori Honda, Masafumi Kudo, Takehiko Matsuo, Hitoshi Okabayashi

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引用次数: 0

Abstract

Background: We aimed to investigate the incidence and risk factors of postoperative acute pancreatitis (PAP) following thoracic aortic surgery with circulatory arrest.

Methods: One hundred fifty-two patients who underwent thoracic aortic surgery with circulatory arrest between February 2015 and March 2023 were retrospectively reviewed. Postoperative acute pancreatitis was defined as the presence of two or more of the following criteria: (1) abdominal pain, (2) postoperative amylase or lipase levels greater than three times the upper limit of normal, and (3) evidence of pancreatitis on postoperative computed tomography (CT) scan. Univariate and multivariate analyses were performed to find risk factors for PAP.

Results: Nine patients (5.9%) developed PAP without mortality. All of the nine patients had elevated pancreatic enzymes and evidence of pancreatitis on CT. They improved with conservative therapy. In multivariate analysis, only cross-clamp time was found to be a significant risk factor for PAP (adjusted odds ratio, 1.04; 95% confidence interval, 1-1.08; p = 0.042).

Conclusion: The incidence of PAP after thoracic aortic surgery with circulatory arrest was 5.9%, and cross-clamp time is an independent risk factor for PAP.

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胸主动脉手术后急性胰腺炎的风险因素。

背景：我们的目的是研究胸主动脉手术后循环停止的术后急性胰腺炎（PAP）的发生率和风险因素：我们旨在研究胸主动脉手术后循环停止状态下术后急性胰腺炎（PAP）的发生率和风险因素：回顾性研究了 2015 年 2 月至 2023 年 3 月期间接受胸主动脉手术并停循环的 152 例患者。术后急性胰腺炎定义为出现以下两个或两个以上标准：(1）腹痛；（2）术后淀粉酶或脂肪酶水平超过正常值上限的三倍；（3）术后计算机断层扫描（CT）有胰腺炎的证据。通过单变量和多变量分析找出胰腺炎的风险因素：结果：9 名患者（5.9%）出现胰腺炎，但无死亡病例。九名患者（5.9%）均有胰酶升高和 CT 显示胰腺炎。他们在接受保守治疗后病情有所好转。在多变量分析中，发现只有交叉钳夹时间是 PAP 的重要风险因素（调整后的几率比为 1.04；95% 置信区间为 1-1.08；P = 0.042）：结论：循环停止的胸主动脉手术后 PAP 发生率为 5.9%，交叉钳夹时间是 PAP 的独立风险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ASIAN CARDIOVASCULAR & THORACIC ANNALS Multiple-

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.