Distribution of biochemical and haematological parameters in an aging population from southern India: A cross-sectional analysis.

IF 2.1 4区医学 Q3 MEDICAL LABORATORY TECHNOLOGY

Annals of Clinical Biochemistry Pub Date : 2024-11-01 Epub Date: 2024-08-12 DOI:10.1177/00045632241267905

Divya N Mallikarjun, Shubham Jain, Palash Kumar Malo, Bratati Kahali, Jonas S Sundarakumar, Latha Diwakar, Vijayalakshmi Ravindranath

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引用次数: 0

Abstract

Background: Examining the distribution of biochemical and haematological tests in different age groups of rural population is necessary to ensure that health care facilities are equipped to address the prevalent health conditions and manage age-related illness effectively. Hence, this study is aimed at seeing the distributions of blood biochemical and haematological parameters in rural population.

Methods: This cross-sectional study investigated the distribution of 26 different haematological and biochemical parameters in longitudinal cohort study (Srinivaspura Aging, NeuoSenescence and COGnition - SANSCOG), from the villages of Srinivaspura, Kolar district, India. A total of 2592 participants (1240 males and 1352 females), aged ≥45 years who are cognitively healthy were included for the analysis. Mean, 2.5^th, 5^th, 25^th, 50^th, 75^th, 95^th and 97.5^th percentiles were calculated for the entire sample. Additionally, median and percentiles were determined for both gender and age categories (45-54, 55-64, 65-74, and ≥75 years).

Results: We observed the distinct distributions of various haematological and biochemical parameters, with elevated levels of glycaemic, lipid, liver, and thyroid parameters.

Conclusion: Findings revealed the notable variations from the established reference ranges, indicating the potential undiagnosed cases and highlighting the gaps in health awareness and health seeking behaviour.

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印度南部老龄人口的生化指标和血液指标分布情况--横断面分析。

背景：为了确保医疗机构有能力应对普遍存在的健康问题，并有效管理与年龄有关的疾病，有必要对农村人口中不同年龄组的生化和血液检测分布情况进行研究。因此，本研究旨在了解农村人口血液生化指标和血液学指标的分布情况：这项横断面研究调查了印度科拉区斯利尼瓦斯普拉村庄的纵向队列研究（斯利尼瓦斯普拉老龄化、神经衰老和COGnition - SANSCOG）中 26 种不同血液和生化指标的分布情况。共有 2592 名年龄≥ 45 岁、认知健康的参与者（男性 1240 人，女性 1352 人）被纳入分析。计算了所有样本的平均值、2.5、5、25、50、75、95 和 97.5 百分位数。此外，还确定了性别和年龄类别（45-54 岁、55-64 岁、65-74 岁和≥75 岁）的中位数和百分位数：结果：我们观察到各种血液和生化参数的不同分布，血糖、血脂、肝脏和甲状腺参数水平升高：结论：研究结果显示了与既定参考范围之间的显著差异，表明了潜在的未确诊病例，并凸显了健康意识和就医行为方面的差距：生化参数医疗保健血液参数印度农村

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来源期刊

Annals of Clinical Biochemistry Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry

CiteScore

5.20

自引率

4.50%

发文量

期刊介绍： Annals of Clinical Biochemistry is the fully peer reviewed international journal of the Association for Clinical Biochemistry and Laboratory Medicine. Annals of Clinical Biochemistry accepts papers that contribute to knowledge in all fields of laboratory medicine, especially those pertaining to the understanding, diagnosis and treatment of human disease. It publishes papers on clinical biochemistry, clinical audit, metabolic medicine, immunology, genetics, biotechnology, haematology, microbiology, computing and management where they have both biochemical and clinical relevance. Papers describing evaluation or implementation of commercial reagent kits or the performance of new analysers require substantial original information. Unless of exceptional interest and novelty, studies dealing with the redox status in various diseases are not generally considered within the journal''s scope. Studies documenting the association of single nucleotide polymorphisms (SNPs) with particular phenotypes will not normally be considered, given the greater strength of genome wide association studies (GWAS). Research undertaken in non-human animals will not be considered for publication in the Annals. Annals of Clinical Biochemistry is also the official journal of NVKC (de Nederlandse Vereniging voor Klinische Chemie) and JSCC (Japan Society of Clinical Chemistry).