Prevalence of Epilepsy in People of Sexual and Gender Minoritized Groups.

IF 20.4 1区医学 Q1 CLINICAL NEUROLOGY

JAMA neurology Pub Date : 2024-09-01 DOI:10.1001/jamaneurol.2024.2243

Emily L Johnson, Esther Bui, Karina Tassiopoulos, Maya Overby Koretzky, Rodrigo Zepeda, Ernesto Gonzalez-Giraldo, Rebecca F Gottesman

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引用次数: 0

Abstract

Importance: Epilepsy is a highly treatable condition for many people, but there are large treatment gaps with suboptimal seizure control in minoritized groups. The sexual and gender minority (SGM) community is at risk for health disparities, yet the burden of epilepsy in this community is not known.

Objective: To estimate the prevalence of active epilepsy among SGM people in the United States.

Design, setting, and participants: This was a cross-sectional, nationally representative survey study of community-dwelling US adults who answered questions about epilepsy, sexual orientation, and gender identity in the 2022 National Health Interview Survey (NHIS).

Exposure: Self-identification of transgender or gender-diverse identity, or sexual orientation including gay, lesbian, bisexual, or other orientation, excluding straight (ie, heterosexual).

Main outcomes and measures: Participants self-reported epilepsy status, medical treatment, seizure frequency, demographic characteristics, sexual orientation, and gender identity. Logistic regression was used to estimate the association of epilepsy with SGM identification.

Results: A total of 27 624 participants (15 050 [54%] women; 3231 [12%] Black; mean [SD] age, 48.2 [18.5] years) completed the NHIS and were included. Active epilepsy was present in 1.2% (95% CI, 1.0%-1.3%) of the population. A higher proportion of SGM adults than non-SGM adults reported active epilepsy (2.4% [95% CI, 1.4%-3.3%] vs 1.1% [95% CI, 1.0%-1.3%], respectively). After adjusting for age, race, ethnicity, income, and education, SGM people were more than twice as likely to report active epilepsy than were non-SGM adults (adjusted odds ratio, 2.14; 95% CI, 1.35-3.37).

Conclusions and relevance: The findings suggest that SGM adults in the United States have a disproportionate prevalence of epilepsy. The reasons for this disparity are likely complex and may be associated with biological and psychosocial determinants of health unique to this population; as such, these individuals are in need of protected access to medical care.

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性和性别少数群体中的癫痫患病率。

重要性：对许多人来说，癫痫是一种非常容易治疗的疾病，但在少数群体中，治疗差距很大，癫痫发作控制不理想。性与性别少数（SGM）群体面临着健康差异的风险，但这一群体的癫痫负担尚不清楚：目的：估计美国性与性别少数群体中活动性癫痫的患病率：这是一项横断面、具有全国代表性的调查研究，调查对象是在 2022 年全国健康访谈调查（NHIS）中回答了有关癫痫、性取向和性别认同问题的美国社区成年人。暴露：变性人或性别多样性身份的自我认同，或性取向，包括男同性恋、女同性恋、双性恋或其他取向，不包括异性恋（即异性恋）：主要结果和测量指标：参与者自我报告的癫痫状况、医疗情况、癫痫发作频率、人口统计学特征、性取向和性别认同。采用逻辑回归法估算癫痫与 SGM 识别的相关性：共有 27 624 名参与者（女性 15 050 人 [54%]；黑人 3 231 人 [12%]；平均 [SD] 年龄 48.2 [18.5] 岁）完成了 NHIS 并被纳入其中。1.2%（95% CI，1.0%-1.3%）的人群患有活动性癫痫。报告有活动性癫痫的 SGM 成人比例高于非 SGM 成人（分别为 2.4% [95% CI, 1.4%-3.3%] vs 1.1% [95% CI, 1.0%-1.3%] ）。在对年龄、种族、民族、收入和教育程度进行调整后，SGM 患者报告活动性癫痫的可能性是非 SGM 成年人的两倍多（调整后的几率比为 2.14；95% CI 为 1.35-3.37）：研究结果表明，美国 SGM 成年人的癫痫发病率过高。造成这种差异的原因可能很复杂，可能与这一人群特有的生物和社会心理健康决定因素有关；因此，这些人需要受到保护才能获得医疗护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JAMA neurology CLINICAL NEUROLOGY-

CiteScore

41.90

自引率

1.70%

发文量

250

期刊介绍： JAMA Neurology is an international peer-reviewed journal for physicians caring for people with neurologic disorders and those interested in the structure and function of the normal and diseased nervous system. The Archives of Neurology & Psychiatry began publication in 1919 and, in 1959, became 2 separate journals: Archives of Neurology and Archives of General Psychiatry. In 2013, their names changed to JAMA Neurology and JAMA Psychiatry, respectively. JAMA Neurology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.