A Bayesian adaptive phase III design for multi-arm trials with time-to-event endpoint for nonproportional hazards utilizing the generalized gamma distribution

IF 0.8 4区数学 Q3 STATISTICS & PROBABILITY

Communications in Statistics-Simulation and Computation Pub Date : 2024-06-24 DOI:10.1080/03610918.2024.2366987

Nadeesha Thewarapperuma, Milind A. Phadnis

引用次数: 0

Abstract

In case of trials with time-to-event endpoints, sample size calculations are well-studied under the assumption of proportional hazards or when the endpoint of interest follows an exponential distri...

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利用广义伽马分布的贝叶斯自适应 III 期多臂试验时间到事件终点非比例危害设计方案

在采用时间到事件终点的试验中，样本量的计算在比例危险假设下或当感兴趣的终点呈指数分布时得到了很好的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Communications in Statistics-Simulation and Computation 数学-统计学与概率论

CiteScore

2.50

自引率

11.10%

发文量

240

审稿时长

6 months

期刊介绍： The Simulation and Computation series intends to publish papers that make theoretical and methodological advances relating to computational aspects of Probability and Statistics. Simulational assessment and comparison of the performance of statistical and probabilistic methods will also be considered for publication. Papers stressing graphical methods, resampling and other computationally intensive methods will be particularly relevant. In addition, special issues dedicated to a specific topic of current interest will also be published in this series periodically, providing an exhaustive and up-to-date review of that topic to the readership.