Reverse Correlation Characterizes More Complete Tinnitus Spectra in Patients

IF 2.7 Q3 ENGINEERING, BIOMEDICAL

IEEE Open Journal of Engineering in Medicine and Biology Pub Date : 2024-07-18 DOI:10.1109/OJEMB.2024.3427318

Nelson V. Barnett;Alec Hoyland;Divya A. Chari;Benjamin Parrell;Adam C. Lammert

{"title":"Reverse Correlation Characterizes More Complete Tinnitus Spectra in Patients","authors":"Nelson V. Barnett;Alec Hoyland;Divya A. Chari;Benjamin Parrell;Adam C. Lammert","doi":"10.1109/OJEMB.2024.3427318","DOIUrl":null,"url":null,"abstract":"<italic>Goal:</i>\n We validate a recent reverse correlation approach to tinnitus characterization by applying it to individuals with clinically-diagnosed tinnitus. \n<italic>Methods:</i>\n Two tinnitus patients assessed the subjective similarity of their non-tonal tinnitus percepts and random auditory stimuli. Regression of the responses onto the stimuli yielded reconstructions which were evaluated qualitatively by playing back resynthesized waveforms to the subjects and quantitatively by response prediction analysis. \n<italic>Results:</i>\n Subject 1 preferred their resynthesis to white noise; subject 2 did not. Response prediction balanced accuracies were significantly higher than chance across subjects: subject 1: 0.5963, subject 2: 0.6922. \n<italic>Conclusion:</i>\n Reverse correlation can provide the foundation for reconstructing accurate representations of complex, non-tonal tinnitus in clinically diagnosed subjects. Further refinements may yield highly similar waveforms to individualized tinnitus percepts.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"5 ","pages":"589-592"},"PeriodicalIF":2.7000,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10602769","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Open Journal of Engineering in Medicine and Biology","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10602769/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Goal: We validate a recent reverse correlation approach to tinnitus characterization by applying it to individuals with clinically-diagnosed tinnitus. Methods: Two tinnitus patients assessed the subjective similarity of their non-tonal tinnitus percepts and random auditory stimuli. Regression of the responses onto the stimuli yielded reconstructions which were evaluated qualitatively by playing back resynthesized waveforms to the subjects and quantitatively by response prediction analysis. Results: Subject 1 preferred their resynthesis to white noise; subject 2 did not. Response prediction balanced accuracies were significantly higher than chance across subjects: subject 1: 0.5963, subject 2: 0.6922. Conclusion: Reverse correlation can provide the foundation for reconstructing accurate representations of complex, non-tonal tinnitus in clinically diagnosed subjects. Further refinements may yield highly similar waveforms to individualized tinnitus percepts.

查看原文本刊更多论文

反向相关性描述了患者更完整的耳鸣频谱

目标：我们将最新的反向相关方法应用于临床确诊的耳鸣患者，从而验证该方法对耳鸣特征的描述。方法两名耳鸣患者评估了他们的非音调耳鸣感知与随机听觉刺激的主观相似性。将反应回归到刺激物上得出重建结果，通过向受试者回放重新合成的波形对其进行定性评估，并通过反应预测分析对其进行定量评估。结果：受试者 1 更喜欢将其重新合成为白噪声；受试者 2 则不喜欢。各受试者的反应预测平衡准确度均明显高于平均值：受试者 1：0.5963；受试者 2：0.6922。结论反向相关可以为临床诊断对象重建复杂、非音调性耳鸣的准确表征奠定基础。进一步的改进可能会产生与个性化耳鸣感知高度相似的波形。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

IEEE Open Journal of Engineering in Medicine and Biology ENGINEERING, BIOMEDICAL-

CiteScore

9.50

自引率

3.40%

发文量

审稿时长

10 weeks

期刊介绍： The IEEE Open Journal of Engineering in Medicine and Biology (IEEE OJEMB) is dedicated to serving the community of innovators in medicine, technology, and the sciences, with the core goal of advancing the highest-quality interdisciplinary research between these disciplines. The journal firmly believes that the future of medicine depends on close collaboration between biology and technology, and that fostering interaction between these fields is an important way to advance key discoveries that can improve clinical care.IEEE OJEMB is a gold open access journal in which the authors retain the copyright to their papers and readers have free access to the full text and PDFs on the IEEE Xplore® Digital Library. However, authors are required to pay an article processing fee at the time their paper is accepted for publication, using to cover the cost of publication.