Retinal Blood Vessels Segmentation With Improved SE-UNet Model

IF 3 4区 计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Yibo Wan, Gaofeng Wei, Renxing Li, Yifan Xiang, Dechao Yin, Minglei Yang, Deren Gong, Jiangang Chen
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引用次数: 0

Abstract

Accurate segmentation of retinal vessels is crucial for the early diagnosis and treatment of eye diseases, for example, diabetic retinopathy, glaucoma, and macular degeneration. Due to the intricate structure of retinal vessels, it is essential to extract their features with precision for the semantic segmentation of medical images. In this study, an improved deep learning neural network was developed with a focus on feature extraction based on the U-Net structure. The enhanced U-Net combines the architecture of convolutional neural networks (CNNs) with SE blocks (squeeze-and-excitation blocks) to adaptively extract image features after each U-Net encoder's convolution. This approach aids in suppressing nonvascular regions and highlighting features for specific segmentation tasks. The proposed method was trained and tested on the DRIVECHASE_DB1 and STARE datasets. As a result, the proposed model had an algorithmic accuracy, sensitivity, specificity, Dice coefficient (Dc), and Matthews correlation coefficient (MCC) of 95.62/0.9853/0.9652, 0.7751/0.7976/0.7773, 0.9832/0.8567/0.9865, 82.53/87.23/83.42, and 0.7823/0.7987/0.8345, respectively, outperforming previous methods, including UNet++, attention U-Net, and ResUNet. The experimental results demonstrated that the proposed method improved the retinal vessel segmentation performance.

利用改进的 SE-UNet 模型进行视网膜血管分割
准确分割视网膜血管对于早期诊断和治疗糖尿病视网膜病变、青光眼和黄斑变性等眼科疾病至关重要。由于视网膜血管结构复杂,因此必须精确提取其特征,以便对医学图像进行语义分割。本研究开发了一种改进的深度学习神经网络,重点是基于 U-Net 结构的特征提取。增强型 U-Net 将卷积神经网络(CNN)的架构与 SE 块(挤压-激发块)相结合,在每个 U-Net 编码器卷积后自适应地提取图像特征。这种方法有助于抑制非血管区域,突出特定分割任务的特征。所提出的方法在 DRIVECHASE_DB1 和 STARE 数据集上进行了训练和测试。结果表明,所提模型的算法准确性、灵敏度、特异性、Dice系数(Dc)和马太相关系数(MCC)分别为 95.62/0.9853/0.9652、0.7751/0.7976/0.7773、0.9832/0.8567/0.9865、82.53/87.23/83.42 和 0.7823/0.7987/0.8345,优于以前的方法,包括 UNet++、attention U-Net 和 ResUNet。实验结果表明,所提出的方法提高了视网膜血管的分割性能。
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来源期刊
International Journal of Imaging Systems and Technology
International Journal of Imaging Systems and Technology 工程技术-成像科学与照相技术
CiteScore
6.90
自引率
6.10%
发文量
138
审稿时长
3 months
期刊介绍: The International Journal of Imaging Systems and Technology (IMA) is a forum for the exchange of ideas and results relevant to imaging systems, including imaging physics and informatics. The journal covers all imaging modalities in humans and animals. IMA accepts technically sound and scientifically rigorous research in the interdisciplinary field of imaging, including relevant algorithmic research and hardware and software development, and their applications relevant to medical research. The journal provides a platform to publish original research in structural and functional imaging. The journal is also open to imaging studies of the human body and on animals that describe novel diagnostic imaging and analyses methods. Technical, theoretical, and clinical research in both normal and clinical populations is encouraged. Submissions describing methods, software, databases, replication studies as well as negative results are also considered. The scope of the journal includes, but is not limited to, the following in the context of biomedical research: Imaging and neuro-imaging modalities: structural MRI, functional MRI, PET, SPECT, CT, ultrasound, EEG, MEG, NIRS etc.; Neuromodulation and brain stimulation techniques such as TMS and tDCS; Software and hardware for imaging, especially related to human and animal health; Image segmentation in normal and clinical populations; Pattern analysis and classification using machine learning techniques; Computational modeling and analysis; Brain connectivity and connectomics; Systems-level characterization of brain function; Neural networks and neurorobotics; Computer vision, based on human/animal physiology; Brain-computer interface (BCI) technology; Big data, databasing and data mining.
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