Cognitive Assessment in children with Congenital Heart Diseases after Cardiac Surgeries

Amir Fawzy Kamal, Fatma Al Zahraa Mostafa, Walaa Fakher, Ahmed Soltan, Mohammed Mohammed Abdelraouf
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Abstract

: Background: Children with congenital heart defects (CHD) now live longer due to advances in surgical and catheter techniques. Their neurodevelopment, including intellectual functioning, has become a major area of concern, attracting both clinical and research interest . Objectives: To assess the cognitive functions in children with CHD after cardiac surgeries and to compare between cyanotic and acyanotic heart disease regarding cognitive functions . Patients and methods: This cross-sectional study included sixty patients with CHD, 30 patients with cyanotic heart disease and 30 patients with acyanotic heart disease, who underwent cardiac surgeries and were examined by Stanford Binet IQ test 5th edition. They were recruited from the post cardiac intervention clinic at Pediatric Hospitals of Cairo University. Results : The mean ± SD age of the children with cyanotic and acyanotic heart diseases was 5±2 and 4 ±1 years respectively (p= 0.345). The IQ was higher among the children with cyanotic compared to those acyanotic heart diseases with mean ± SD (range) of 85.4 ± 12 and 99.9 ± 13 respectively (p= 0.0001). IQ was not influenced by age at operation (p= 0. 171), type of operation (p= 0. 381), sex (p= 0.323), or oxygen saturation (p= 0.308). Mean ±SD IQ of those with cyanotic CHD who underwent closed and open heart surgeries was 88±11 and 84±13 respectively (p= 0.381), and in acyanotic group was 104±14 and 98±13 respectively (p= 0.323). Conclusion: Children with congenital heart defects may have cognitive dysfunction. Children with cyanotic CHD have significantly lower IQ values than those with acyanotic CHD. No significant differences in IQ were found between patients who underwent closed and open heart surgery.
先天性心脏病儿童心脏手术后的认知能力评估
:背景:由于手术和导管技术的进步,先天性心脏缺陷(CHD)患儿的寿命延长了。他们的神经发育(包括智力功能)已成为一个主要关注领域,引起了临床和研究的兴趣。研究目的评估心脏手术后先天性心脏病患儿的认知功能,并比较紫绀型心脏病和无紫绀型心脏病患儿的认知功能。患者和方法这项横断面研究包括 60 名接受心脏手术的先天性心脏病患者,其中 30 名为紫绀型心脏病患者,30 名为无紫绀型心脏病患者。他们是从开罗大学儿科医院心脏介入术后门诊招募的。结果:紫绀型和无紫绀型心脏病患儿的平均年龄(± SD)分别为 5±2 岁和 4±1 岁(P= 0.345)。紫绀型心脏病患儿的智商高于青紫型心脏病患儿,平均值(± SD)分别为 85.4 ± 12 和 99.9 ± 13(P= 0.0001)。智商不受手术年龄(p= 0. 171)、手术类型(p= 0. 381)、性别(p= 0.323)或血氧饱和度(p= 0.308)的影响。接受闭合性和开放性心脏手术的紫绀型先天性心脏病患者的智商平均值(±SD)分别为(88±11)和(84±13)(P= 0.381),无紫绀组患者的智商平均值(±SD)分别为(104±14)和(98±13)(P= 0.323)。结论先天性心脏病患儿可能存在认知功能障碍。青紫型先天性心脏病患儿的智商值明显低于无青紫型先天性心脏病患儿。接受闭合性和开放性心脏手术的患者智商没有明显差异。
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