A Study is Examining How Postpartum Pain after Cesarean Section (SC) Can be Reduced by Boosting Levels of β-endorphin Through Electroacupuncture Stimulation at The Specified Points LI4 and SP6

Q3 Pharmacology, Toxicology and Pharmaceutics
Nurul Azizah, Budi Santoso, A. Abdurachman, H. Hidayati, Ario Imandiri
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Abstract

Background : The physical healing process following a cesarean section surgery can induce anxiety and physiological stress due to wound pain, potentially impairing patient mobility and necessitating the administration of analgesic therapy. Pharmacological treatment sometimes proves insufficient or contraindicated for postpartum cesarean section patients, highlighting the need for non-pharmacological alternative therapies. Objective : This study aims to investigate the impact of electroacupuncture (EA) stimulation at specific points SP6 and LI4 using frequencies of 30, 50, and 100 Hz on reducing pain intensity and increasing levels of the hormone β -endorphin in postpartum cesarean section patients. Method : In this research, 144 postpartum cesarean section participants meeting inclusion criteria are divided into 8 groups, comprising intervention and control groups, utilizing a randomized control trial (RCT) technique. Pain intensity is measured using the pain numeric rating scale (PNRS), while levels of β -endorphin are analyzed through blood samples using the enzyme-linked immunosorbent assay (ELISA) method to compare outcomes before and after intervention. Result: The analysis of the intervention group receiving electroacupuncture at specific points LI4 and SP6 has demonstrated effectiveness in reducing pain by increasing levels of the hormone β -endorphin, in comparison to the control group, with significant findings. Conclusion : The findings of this study show that electroacupuncture intervention in postpartum cesarean section patients can stimulate an increase in β -endorphin hormone levels and effectively reduce postpartum cesarean section pain intensity
一项研究探讨如何通过电针刺激特定穴位 LI4 和 SP6 来提高 β-内啡肽水平,从而减轻剖腹产(SC)后的产后疼痛
背景:剖腹产手术后的身体愈合过程会因伤口疼痛而引起焦虑和生理压力,可能会影响患者的活动能力,因此有必要进行镇痛治疗。对于产后剖宫产患者来说,药物治疗有时被证明是不够的或禁忌的,这就凸显了对非药物替代疗法的需求。目的:本研究旨在探讨电针刺激特定穴位 SP6 和 LI4(频率分别为 30、50 和 100 Hz)对减轻产后剖宫产患者疼痛强度和提高激素 β - 内啡肽水平的影响。方法:本研究采用随机对照试验(RCT)技术,将符合纳入标准的 144 名产后剖腹产参与者分为 8 组,包括干预组和对照组。干预组采用疼痛数字评分量表(PNRS)测量疼痛强度,对照组采用酶联免疫吸附试验(ELISA)方法通过血液样本分析β-内啡肽水平,比较干预前后的结果。结果与对照组相比,在特定穴位 LI4 和 SP6 上接受电针治疗的干预组通过提高激素 β - 内啡肽的水平,有效减轻了疼痛,分析结果具有显著性。结论:本研究结果表明,对产后剖宫产患者进行电针干预可刺激β-内啡肽激素水平的升高,有效降低产后剖宫产疼痛强度。
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来源期刊
Pharmacognosy Journal
Pharmacognosy Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
2.20
自引率
0.00%
发文量
151
期刊介绍: In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs. Pharmacognosy Journal (Phcog J.) is one of the six journals published by Phcog.Net, Each issue covers different topics in natural product drug discovery, and also publishes manuscripts that describe pharmacognostic investigations, evaluation reports, methods, techniques and applications of all forms of medicinal plant research
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