A Case Report of Trueperella bernardiae Pelvic Osteomyelitis and Sepsis: Literature Review of Trueperella bernardiae Infections

Saliha Saleem, William Roland, Abdullah Lodhi
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Abstract

Abstract Introduction: Trueperella bernardiae is a gram-negative coccobacilli that was initially categorized as coryneform bacteria, and thus frequently, it was not further investigated as a pathogenic organism. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) has revolutionized the identification of bacteria, including T. bernardiae. Now case reports for T. bernardiae infections are starting to be reported, but it remains a rare pathogen for infections. Case Presentation: Here we are reporting a rare case of T. bernardiae bacteremia, presenting with sepsis and imaging finding showing pelvic septic arthritis, micro-abscesses, and osteomyelitis. It would have likely started as urinary tract infection, followed by osteomyelitis and bacteremia. The patient was managed with intravenous vancomycin. The follow-up clinic visit showed clinical improvement. This article also provides a brief literature review of T. bernardiae infections. Conclusion: T. bernardiae infections are rare but have clinical significance. This case adds another case to the literature regarding T. bernardiae infections and especially highlights the point that they can present with a more serious presentation like sepsis. MALDI-TOF helps in the identification of these rare pathogens.
骨盆骨髓炎和败血症的布鲁氏菌病例报告:布鲁氏菌感染文献综述
摘要 引言:Trueperella bernardiae 是一种革兰氏阴性球菌,最初被归类为棒状杆菌,因此经常不被作为致病菌进一步研究。基质辅助激光解吸电离飞行时间(MALDI-TOF)技术为鉴定细菌(包括伯纳德氏菌)带来了革命性的变化。现在,有关伯纳氏菌感染的病例报告开始出现,但它仍然是一种罕见的感染病原体。病例介绍:这里我们报告的是一例罕见的伯纳德氏菌菌血症病例,患者出现败血症,影像学检查显示骨盆化脓性关节炎、微小脓肿和骨髓炎。起初很可能是尿路感染,随后出现骨髓炎和菌血症。患者接受了万古霉素静脉注射治疗。随访显示临床症状有所改善。本文还简要回顾了有关伯纳德氏菌感染的文献。结论伯纳德氏菌感染很少见,但具有临床意义。本病例为有关伯纳德氏菌感染的文献再添一例,特别强调了伯纳德氏菌感染可能会出现败血症等更严重的症状。MALDI-TOF 有助于鉴定这些罕见的病原体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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