Polymer-Based Wound Dressings Loaded with Essential Oil for the Treatment of Wounds: A Review

Pharmaceuticals Pub Date : 2024-07-05 DOI:10.3390/ph17070897

Bruna Michele A. de B. Buriti, P. L. Figueiredo, M. F. Passos, J. D. da Silva

{"title":"Polymer-Based Wound Dressings Loaded with Essential Oil for the Treatment of Wounds: A Review","authors":"Bruna Michele A. de B. Buriti, P. L. Figueiredo, M. F. Passos, J. D. da Silva","doi":"10.3390/ph17070897","DOIUrl":null,"url":null,"abstract":"Wound healing can result in complex problems, and discovering an effective method to improve the healing process is essential. Polymeric biomaterials have structures similar to those identified in the extracellular matrix of the tissue to be regenerated and also avoid chronic inflammation, and immunological reactions. To obtain smart and effective dressings, bioactive agents, such as essential oils, are also used to promote a wide range of biological properties, which can accelerate the healing process. Therefore, we intend to explore advances in the potential for applying hybrid materials in wound healing. For this, fifty scientific articles dated from 2010 to 2023 were investigated using the Web of Science, Scopus, Science Direct, and PubMed databases. The principles of the healing process, use of polymers, type and properties of essential oils and processing techniques, and characteristics of dressings were identified. Thus, the plants Syzygium romanticum or Eugenia caryophyllata, Origanum vulgare, and Cinnamomum zeylanicum present prospects for application in clinical trials due to their proven effects on wound healing and reducing the incidence of inflammatory cells in the site of injury. The antimicrobial effect of essential oils is mainly due to polyphenols and terpenes such as eugenol, cinnamaldehyde, carvacrol, and thymol.","PeriodicalId":509865,"journal":{"name":"Pharmaceuticals","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceuticals","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/ph17070897","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Wound healing can result in complex problems, and discovering an effective method to improve the healing process is essential. Polymeric biomaterials have structures similar to those identified in the extracellular matrix of the tissue to be regenerated and also avoid chronic inflammation, and immunological reactions. To obtain smart and effective dressings, bioactive agents, such as essential oils, are also used to promote a wide range of biological properties, which can accelerate the healing process. Therefore, we intend to explore advances in the potential for applying hybrid materials in wound healing. For this, fifty scientific articles dated from 2010 to 2023 were investigated using the Web of Science, Scopus, Science Direct, and PubMed databases. The principles of the healing process, use of polymers, type and properties of essential oils and processing techniques, and characteristics of dressings were identified. Thus, the plants Syzygium romanticum or Eugenia caryophyllata, Origanum vulgare, and Cinnamomum zeylanicum present prospects for application in clinical trials due to their proven effects on wound healing and reducing the incidence of inflammatory cells in the site of injury. The antimicrobial effect of essential oils is mainly due to polyphenols and terpenes such as eugenol, cinnamaldehyde, carvacrol, and thymol.

查看原文本刊更多论文

含精油的聚合物伤口敷料用于治疗伤口：综述

伤口愈合可能导致复杂的问题，因此必须找到一种有效的方法来改善愈合过程。高分子生物材料具有与待再生组织细胞外基质相似的结构，还能避免慢性炎症和免疫反应。为了获得智能、有效的敷料，我们还使用了生物活性剂（如精油）来促进各种生物特性，从而加快愈合过程。因此，我们打算探索在伤口愈合中应用混合材料的潜力。为此，我们使用 Web of Science、Scopus、Science Direct 和 PubMed 数据库调查了 2010 年至 2023 年的 50 篇科学文章。确定了愈合过程的原理、聚合物的使用、精油的类型和特性、加工技术以及敷料的特点。因此，浪漫草（Syzygium romanticum）或欧栀子（Eugenia caryophyllata）、牛至（Origanum vulgare）和肉桂（Cinnamomum zeylanicum）等植物被证明对伤口愈合和减少受伤部位炎症细胞的发生率有显著效果，有望应用于临床试验。精油的抗菌作用主要来自多酚和萜烯，如丁香酚、肉桂醛、香芹酚和百里酚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pharmaceuticals

自引率

0.00%

发文量