Integrated Management of Post-Myocardial Infarction Patients Using Genetic Analysis and Remote Control

Zhalolov Bakhrom Zukhriddinovich
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Abstract

Coronary heart disease (CHD) remains a leading cause of mortality and morbidity worldwide, particularly due to complications following myocardial infarction (MI). Despite advancements in therapeutic strategies, the prognosis for MI patients varies significantly, necessitating a comprehensive approach that integrates genetic and non-genetic factors. This study addresses the knowledge gap by evaluating the influence of genetic polymorphisms and non-genetic factors on the 12-month prognosis of MI patients. Using a cohort of 250 post-MI patients, we conducted genetic analysis on polymorphisms of the AGT, ADRB1, APOE, LPL, and CYP2C19 genes and assessed their correlation with clinical outcomes using modern statistical methods. Our findings indicate significant associations between specific gene polymorphisms and patient prognosis, highlighting the importance of personalized medicine. The results suggest that incorporating genetic analysis into the management of MI patients can improve survival rates and inform targeted therapeutic interventions, offering a novel approach to enhancing patient care in clinical settings.
利用基因分析和远程控制对心肌梗死后患者进行综合管理
冠心病(CHD)仍然是全球死亡和发病的主要原因,尤其是心肌梗塞(MI)后的并发症。尽管治疗策略取得了进步,但心肌梗死患者的预后仍有很大差异,因此需要一种综合了遗传和非遗传因素的全面方法。本研究通过评估遗传多态性和非遗传因素对心肌梗死患者 12 个月预后的影响,填补了这一知识空白。我们使用 250 名心肌梗死后患者的队列,对 AGT、ADRB1、APOE、LPL 和 CYP2C19 基因的多态性进行了遗传分析,并使用现代统计方法评估了它们与临床预后的相关性。我们的研究结果表明,特定基因多态性与患者预后之间存在明显关联,凸显了个性化医疗的重要性。结果表明,将基因分析纳入心肌梗死患者的管理可提高存活率,并为有针对性的治疗干预提供信息,为加强临床环境中的患者护理提供了一种新方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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