Assessment and Empirical Treatment of Chronic Abdominal Pain from Suspected Helicobacter Pylori Infection In a Remote Setting

Sean Ferguson
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Abstract

The prevalence of Helicobacter Pylori (H. Pylori) remains globally high, with an estimated 50% of the words population believed to be infected. Despite the continually high incident rates of infection 90% of those infected remain asymptomatic. H.Pylori is a gram-negative, microaerophilic bacteria, mostly found in stomach of affected individuals that causes inflammation and ulceration.  Definitive routes of transmission and subsequent infection are still debated. The most likely mechanism of transmission is thought to be intrafamilliar, this encapsulates fecal-oral, gastric-oral, oral-oral and sexual vectors. Contaminated foods and water sources are also highly likely mechanisms of transmission. Therefore in developing countries with poor sanitation, potentially contaminated water sources and regions with social-economic hardship experience increased symptomatic cases of H.Pylori. 
偏远地区疑似幽门螺杆菌感染所致慢性腹痛的评估和经验性治疗
幽门螺杆菌(H. Pylori)的发病率在全球范围内居高不下,据估计有 50%的人口受到感染。尽管感染率居高不下,但90%的感染者仍无症状。幽门螺杆菌是一种革兰氏阴性、嗜微酵母菌,主要存在于患者的胃部,会引起炎症和溃疡。关于传播和后续感染的明确途径仍存在争议。最可能的传播机制被认为是家庭内部传播,包括粪-口、胃-口、口-口和性媒介。受污染的食物和水源也很可能是传播机制。因此,在卫生条件差、水源可能受到污染的发展中国家和社会经济困难的地区,幽门螺杆菌的无症状病例会增加。
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