Using the OPUF approach to create a value set for the EQ-HWB-S: An exploratory feasibility study

PP Schneider, Kristina Ludwig, Ole Marten, E. McDool, T. Peasgood, Nancy Devlin, Koonal Shah, John Brazier, Wolfgang Greiner, C. Mukuria
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Abstract

Objectives The EQ-HWB-S (EQ Health and Wellbeing Short version) is a new generic measure of health, social care and carer related quality of life, specifically developed to generate utility values. However, its nine dimensions pose a challenge for creating value sets using traditional elicitation techniques, such as time trade-off. A promising alternative method, called Online elicitation of Personal Utility Functions (OPUF) has recently been proposed. The aim of this study was to test the feasibility of using OPUF to create a value set for the EQ-HWB-S. Methods We adapted the OPUF tool for the EQ-HWB-S, and piloted it in convenience samples from the UK and Germany. We then conducted an explorative valuation study in both countries in March 2023. We recruited a total of 658 respondents, in four samples: UK (n=328) and German (n=110) general population, and German rheumatic disease (n=110) and diabetes (n=110) patients. Feasibility was assessed based on completion times, data quality, logical consistency, and respondents’ feedback. A demo version of the English OPUF survey is available at: https://valorem.health/eqen-demo Results The OPUF approach was found to be feasible. Most respondents completed the survey in around 15 minutes and found it easy to complete. We derived well-ordered value set coefficients. Pain, mobility, and daily activities were the three most important dimensions in all four samples. The OPUF-derived UK value set differed in several notable ways from a UK value set derived using traditional elicitation methods. Conclusion This study has demonstrated the feasibility of using OPUF to create a value set for the EQ-HWB-S in four relatively small samples including two patient groups. While further validation is needed, our results suggest that OPUF might be a viable alternative or supplement to the traditional valuation techniques for eliciting health state preferences.
使用 OPUF 方法为 EQ-HWB-S 创建价值集:探索性可行性研究
目的 EQ-HWB-S (EQ 健康与幸福简易版)是一种新的通用测量方法,用于测量与健康、社会护理和照护者相关的生活质量,专门用于生成效用值。然而,它的九个维度对使用传统诱导技术(如时间权衡)创建价值集构成了挑战。最近有人提出了一种很有前途的替代方法,称为 "个人效用函数在线激发法"(OPUF)。本研究旨在测试使用 OPUF 创建 EQ-HWB-S 价值集的可行性。方法 我们为 EQ-HWB-S 改编了 OPUF 工具,并在英国和德国的便利样本中进行了试用。然后,我们于 2023 年 3 月在这两个国家开展了一项探索性估值研究。我们在四个样本中共招募了 658 名受访者:英国(n=328)和德国(n=110)普通人群,以及德国风湿病(n=110)和糖尿病(n=110)患者。根据完成时间、数据质量、逻辑一致性和受访者的反馈,对可行性进行了评估。英语 OPUF 调查的演示版可在以下网址获得: https://valorem.health/eqen-demo 结果 OPUF 方法是可行的。大多数受访者都在 15 分钟左右完成了调查,并认为很容易完成。我们得出了井然有序的值集系数。在所有四个样本中,疼痛、活动能力和日常活动是三个最重要的维度。OPUF 得出的英国价值集在多个方面与使用传统诱导方法得出的英国价值集存在明显差异。结论 本研究证明了在四个相对较小的样本(包括两个患者群体)中使用 OPUF 创建 EQ-HWB-S 价值集的可行性。虽然还需要进一步验证,但我们的研究结果表明,OPUF 可以替代或补充传统的健康状况偏好评估技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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