Correlation between the GRACE Risk Score and the SYNTAX Score in Patients with Non-ST-Segment Elevation Myocardial Infarction

University Heart Journal Pub Date : 2024-07-11 DOI:10.3329/uhj.v3i1.73749

S. N. Huda, Mohammad Faisal, Ibn Kabir, MD. Tasnim MOSTASHIRUL HAQUE, Afm Azim Alam, Swadesh Kumar Anwar, SK SAHA, MD Nafis Kabir, MD. Fakrul H.N. ASHIQUR RAHMAN, Islam Khaled, Chaudhury TANJIMA PARVIN, MD. Rasul MESHKAT AHMED, Amin

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Abstract

Background: The GRACE risk score is a valid clinical tool to risk stratify patients with non-ST-segment elevation myocardial infarction (NSTEMI). The SYNTAX score is a comprehensive angiographic grading tool to determine the anatomic complexity of coronary artery disease. Predicting the SYNTAX score before a coronary angiogram (CAG) can help with patient counseling, optimization of planning, and preparation for possible complex percutaneous procedures or CABG in patients with NSTEMI. Objective: The objective of this study is to determine the correlation between the GRACE risk score and the SYNTAX score in patients with NSTEMI. Materials and Methods: A total of 52 patients with NSTEMI undergoing coronary angiography were enrolled in this study. According to the calculated GRACE score on admission, patients were divided into a low-risk group (GRACE score ≤108), an intermediate-risk group (GRACE score = 109–140), and a high-risk group (GRACE score > 140). After coronary angiography, the SYNTAX score was calculated. The correlation between the scores was determined by Pearson’s correlation test. Results: The mean SYNTAX score in the low GRACE risk group was 9.5 ± 5.1, in the intermediate GRACE risk group it was 12.5 ± 7.6, and in the high GRACE risk group it was 18.5 ± 8.9, and the differences were significant (P value = 0.005). There was a significant positive correlation (r = 0.515, p = <0.001) between the GRACE risk score and the SYNTAX score in patients with NSTEMI. Conclusion: Our study demonstrates that in NSTEMI patients, the GRACE risk score has a significant positive correlation with the SYNTAX score. University Heart Journal 2023; 19(2): 49-54

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非 ST 段抬高型心肌梗死患者的 GRACE 风险评分与 SYNTAX 评分之间的相关性

背景：GRACE 风险评分是对非 ST 段抬高型心肌梗死（NSTEMI）患者进行风险分层的有效临床工具。SYNTAX 评分是一种全面的血管造影分级工具，用于确定冠状动脉疾病的解剖复杂性。在冠状动脉造影（CAG）前预测 SYNTAX 评分有助于为 NSTEMI 患者提供患者咨询、优化计划并为可能的复杂经皮手术或 CABG 做好准备：本研究旨在确定 GRACE 风险评分与 SYNTAX 评分在 NSTEMI 患者中的相关性：本研究共纳入52名接受冠状动脉造影术的NSTEMI患者。根据入院时计算出的 GRACE 评分，患者被分为低危组（GRACE 评分 ≤108）、中危组（GRACE 评分 = 109-140）和高危组（GRACE 评分 > 140）。冠状动脉造影后，计算 SYNTAX 评分。得分之间的相关性通过皮尔逊相关检验确定：低GRACE风险组的平均SYNTAX评分为（9.5 ± 5.1）分，中GRACE风险组为（12.5 ± 7.6）分，高GRACE风险组为（18.5 ± 8.9）分，差异显著（P值= 0.005）。在NSTEMI患者中，GRACE风险评分与SYNTAX评分之间存在明显的正相关性（r = 0.515，P = <0.001）：我们的研究表明，在NSTEMI患者中，GRACE风险评分与SYNTAX评分呈显著正相关：49-54

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University Heart Journal

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