The Use of Extracorporeal Membrane Oxygenation in a Patient with Septic Myocarditis in the Postpartum Period

I. A. Belyaev, O. Korkin, O. G. Malkova, A. L. Levit
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Abstract

Introduction. Septic myocarditis is a rare disease (from 10 to 22 cases per 100 000 people). The cause of death is usually acute heart failure, hemodynamically significant cardiac arrhythmias, or thromboembolism. Patients in critical condition suffering from infectious myocarditis require massive cardiotonic support to maintain the necessary cardiac output with reduced myocardial contractile function, which leads to an increase in the need for cardiomyocytes for oxygen and aggravates their damage. Veno-arterial extracorporeal membrane oxygenation (ECMO) allows partial or complete replacement of cardiac function and reduces the dose of inotropic drugs, improve oxygen delivery and thereby contribute to the rapid restoration of cardiac function.The purpose of this publication is to demonstrate in a clinical case the successful experience of ECMO in the treatment of a patient with septic myocarditis in the early postpartum period.Materials and methods. A 28-year-old patient, data from medical records at the previous stages of treatment and at the Sverdlovsk Regional Clinical Hospital No. 1.Results. On the third day of treatment, the patient’s condition worsened due to the progression of cardiovascular and respiratory failure. A veno-arterial ECMO procedure was initiated, which lasted 6 days.Discussion. Positive dynamics in the patient’s condition were observed during six days of ECMO (normalization of echocardiography parameters, levels of cardiac enzymes and natriuretic peptide).Conclusion. Veno-arterial ECMO as a temporary method of mechanical support of the left ventricle and prosthetic pulmonary function can be successfully used until their recovery in patients with septic myocarditis in the postpartum period.
在一名产后化脓性心肌炎患者身上使用体外膜氧合技术
导言化脓性心肌炎是一种罕见疾病(每 10 万人中有 10 到 22 例)。死亡原因通常是急性心力衰竭、血流动力学显著性心律失常或血栓栓塞。感染性心肌炎危重病人需要大量的强心支持,以维持必要的心输出量,但心肌收缩功能减弱,导致心肌细胞对氧气的需求增加,加重了心肌细胞的损伤。静脉-动脉体外膜肺氧合(ECMO)可部分或完全替代心脏功能,减少肌力药物剂量,改善氧输送,从而有助于快速恢复心脏功能。本刊物旨在通过一个临床病例,展示 ECMO 治疗一名产后早期化脓性心肌炎患者的成功经验。一名 28 岁的患者,斯维尔德洛夫斯克地区第一临床医院前几个治疗阶段的病历资料。治疗第三天,由于心血管和呼吸衰竭的发展,患者病情恶化。于是开始了静脉-动脉 ECMO 程序,该程序持续了 6 天。在 6 天的 ECMO 治疗中,患者的病情出现了积极的变化(超声心动图参数、心肌酶和钠尿肽水平恢复正常)。静脉-动脉 ECMO 作为左心室和人工肺功能机械支持的临时方法,可成功用于产后化脓性心肌炎患者,直至其康复。
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