Comparison of laser induced corneal injury thresholds with safety limits for the wavelength range of 1200–1500 nm

K. Schulmeister, B. Stuck
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Abstract

A computer model predicting thresholds for laser induced corneal injury was used to systematically analyze wavelength, pulse duration, and beam diameter dependencies for wavelengths between 1200 and 1500 nm, for the exposure duration regime of 10 μs to 100 s. The thresholds were compared with the maximum permissible exposure (MPE) values to protect the cornea as specified in ANSI Z136.1-2022, ICNIRP 2013, and IEC 60825-1:2014. In the wavelength range between 1200 and 1400 nm, the dominant hazard transitions from the retina to the cornea. Consequently, limits are needed to protect both the cornea and the retina. In the lower wavelength range, the retinal limits are more conservative, while in the higher wavelength range, the corneal limits are lower. Comparison with injury thresholds shows that ANSI MPEs include a large safety margin for all wavelengths. Due to the 7 mm aperture stop defined in IEC 60825-1, levels permitted by the Class 3B limit exceed the predicted injury thresholds for small beam diameters and wavelengths between approximately 1350 and 1400 nm. The Class 3B limit does not appear to be sufficiently protective for these conditions. For skin MPEs, the margin between corneal injury thresholds and MPEs decreases steadily for wavelengths approaching 1400 nm. However, normal eye movements can be expected to reduce the effective exposure so that skin MPEs may serve as adequate limits to protect the cornea for wavelengths less than 1400 nm until a specific limit to protect the cornea is promulgated by ICNIRP.
波长范围为 1200-1500 纳米的激光诱导角膜损伤阈值与安全限值的比较
利用预测激光诱导角膜损伤阈值的计算机模型,系统分析了波长在 1200 至 1500 nm 之间的激光在 10 μs 至 100 s 暴露持续时间范围内的波长、脉冲持续时间和光束直径相关性。将阈值与 ANSI Z136.1-2022、ICNIRP 2013 和 IEC 60825-1:2014 中规定的保护角膜的最大允许暴露值 (MPE) 进行了比较。在 1200 和 1400 纳米之间的波长范围内,主要危害从视网膜转移到角膜。因此,需要同时保护角膜和视网膜的限值。在较低的波长范围内,视网膜的限值较为保守,而在较高的波长范围内,角膜的限值较低。与伤害阈值的比较表明,ANSI MPE 在所有波长上都有很大的安全余量。由于 IEC 60825-1 中定义的 7 毫米孔径止挡,3B 级限值允许的水平超过了小光束直径和大约 1350 至 1400 纳米波长的预测伤害阈值。在这些情况下,3B 级限值似乎不足以起到保护作用。对于皮肤 MPE,当波长接近 1400 nm 时,角膜损伤阈值与 MPE 之间的差值会逐渐减小。不过,正常的眼球运动可以减少有效照射,因此在国际非电离辐射防护委员会颁布保护角膜的具体限值之前,皮肤 MPE 可以作为波长小于 1400 nm 时保护角膜的适当限值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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