EIT probe based intraoperative tissue inspection for minimally invasive surgery

IF 2.7 3区 工程技术 Q1 ENGINEERING, MULTIDISCIPLINARY
Jing Guo, Baiyang Zhuang, Renkai Li, Zexuan Lin, Zhuoqi Cheng, Haifang Lou
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Abstract

Electrical Impedance Tomography (EIT) has become an integral component in the repertoire of medical imaging techniques, particularly due to its non-invasive nature and real-time imaging capabilities. Despite its potential, the application of EIT in Minimally Invasive Surgery (MIS) has been hindered by a lack of specialized electrode probes. Existing designs often compromise between invasiveness and spatial sensitivity: probes small enough for MIS often fail to provide detailed imaging, while those offering greater sensitivity are impractically large for use through a surgical trocar. Addressing this challenge, our study presents a breakthrough in EIT probe design. The open electrode probe we have developed features a line of 16 electrodes, thoughtfully arrayed to balance the spatial demands of MIS with the need for precise imaging. Employing an advanced EIT reconstruction algorithm, our probe not only captures images that reflect the electrical characteristics of the tissues but also ensures the homogeneity of the test material is accurately represented.The versatility of our probe is demonstrated by its capacity to generate high-resolution images of subsurface anatomical structures, a feature particularly valuable during MIS where direct visual access is limited. Surgeons can rely on intraoperative EIT imaging to inform their navigation of complex anatomical landscapes, enhancing both the safety and efficacy of their procedures. Through rigorous experimental validation using ex vivo tissue phantoms, we have established the probe's proficiency. The experiments confirmed the system's high sensitivity and precision, particularly in the critical tasks of subsurface tissue detection and surgical margin delineation.These capabilities manifest the potential of our probe to revolutionize the field of surgical imaging, providing a previously unattainable level of detail and assurance in MIS procedures.
基于 EIT 探头的术中组织检查,用于微创手术
电阻抗断层扫描(EIT)已成为医学成像技术中不可或缺的组成部分,特别是由于其非侵入性和实时成像功能。尽管电阻抗断层扫描具有很大的潜力,但由于缺乏专用的电极探头,它在微创手术(MIS)中的应用一直受到阻碍。现有的设计往往在侵袭性和空间灵敏度之间折衷:对于微创手术来说,足够小的探头往往无法提供详细的成像,而那些灵敏度更高的探头又太大,无法通过手术套管使用。为了应对这一挑战,我们的研究在 EIT 探头设计方面取得了突破性进展。我们开发的开放式电极探头由 16 个电极组成,这些电极经过精心排列,既能满足 MIS 的空间要求,又能满足精确成像的需要。我们的探针采用先进的 EIT 重建算法,不仅能捕捉到反映组织电特性的图像,还能确保准确反映测试材料的均匀性。我们探针的多功能性体现在它能生成表面下解剖结构的高分辨率图像,这在 MIS 过程中特别有价值,因为直接观察受到限制。外科医生可以依靠术中 EIT 成像为其复杂解剖结构的导航提供信息,从而提高手术的安全性和有效性。通过使用体外组织模型进行严格的实验验证,我们确定了该探针的能力。实验证实了该系统的高灵敏度和高精确度,尤其是在表皮下组织检测和手术边缘划定等关键任务中。这些功能表明,我们的探针有可能彻底改变外科成像领域,为 MIS 手术提供以前无法实现的细节和保证。
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来源期刊
Measurement Science and Technology
Measurement Science and Technology 工程技术-工程:综合
CiteScore
4.30
自引率
16.70%
发文量
656
审稿时长
4.9 months
期刊介绍: Measurement Science and Technology publishes articles on new measurement techniques and associated instrumentation. Papers that describe experiments must represent an advance in measurement science or measurement technique rather than the application of established experimental technique. Bearing in mind the multidisciplinary nature of the journal, authors must provide an introduction to their work that makes clear the novelty, significance, broader relevance of their work in a measurement context and relevance to the readership of Measurement Science and Technology. All submitted articles should contain consideration of the uncertainty, precision and/or accuracy of the measurements presented. Subject coverage includes the theory, practice and application of measurement in physics, chemistry, engineering and the environmental and life sciences from inception to commercial exploitation. Publications in the journal should emphasize the novelty of reported methods, characterize them and demonstrate their performance using examples or applications.
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