Zheyao Li, Lei Ju, Ruipeng Bao, Xinbo Lin, Teng Wang, Xinhong Yu
{"title":"N-heterocyclic carbene-catalyzed reassembling of dibenzyl ethers: facile access to α-hydroxy ketones","authors":"Zheyao Li, Lei Ju, Ruipeng Bao, Xinbo Lin, Teng Wang, Xinhong Yu","doi":"10.1055/a-2367-2572","DOIUrl":null,"url":null,"abstract":"A novel one-pot cascade process of oxidation-initiated N-heterocyclic carbene-catalyzed reintegration of dibenzyl ethers has been developed for the first time. This protocol allows straightforward access to α-hydroxy ketones from dibenzyl ethers. It is noteworthy that the present method is the first attempt to synthesize benzoin by utilization of dibenzyl ethers.","PeriodicalId":509029,"journal":{"name":"Synlett","volume":"5 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synlett","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2367-2572","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A novel one-pot cascade process of oxidation-initiated N-heterocyclic carbene-catalyzed reintegration of dibenzyl ethers has been developed for the first time. This protocol allows straightforward access to α-hydroxy ketones from dibenzyl ethers. It is noteworthy that the present method is the first attempt to synthesize benzoin by utilization of dibenzyl ethers.