A Study of Predictors of Failure of Nonoperative Management of Ileocolic Intussusception in Children.

Jibreel Y Shah, Imad Banday, Hanna Z Hamdani, Mohd Fazlul Haq, Fazl Q Parray, Meeran Banday, Gowhar Aziz Bhat
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Abstract

Background: Surgery remains the mainstay in treating intussusception in developing nations. A correspondingly high bowel resection rate exists despite a shift to nonoperative reduction in high-income countries. We aimed to study the clinical profile of the patients with intussusception presenting to our hospital and to assess the clinical and radiological predictors of success or failure of nonoperative management of intussusception.

Materials and methods: This prospective study was conducted in the Department of Pediatric Surgery over a period of 3 years and included a total of 118 patients who presenting to our emergency division with features suggestive of intussusception and were managed accordingly either with hydrostatic reduction or by surgical intervention.

Results: We observed that the majority of the patients were males (65.5%). The mean age was 13.54 months. Intermittent pain was the most common symptom. Both pain and vomiting did not affect the outcome. Lab parameters like raised total leukocyte counts (TLC), C-reactive protein (CRP) and lactate levels were significantly associated with failure of hydrostatic reduction. Patients with air fluid levels on X-ray were more likely to end up in surgery. Ultrasound findings of bowel wall edema, aperistaltic gut loops and a pathological lead point was associated with failure of hydrostatic reduction as well. The overall success rate of hydrostatic reduction was 85.5%.

Conclusion: Hydrostatic reduction of intussusception is a safe and effective method of management of intussusception whenever indicated. Factors that might reduce the chance of its success include continuous pain, irritability, tenderness, deranged lab parameters like TLC, CRP and lactate levels, air fluid levels on X-ray, bowel wall edema, aperistalsis and the presence of a lead point.

How to cite this article: Shah JY, Banday I, Hamdani HZ, et al. A Study of Predictors of Failure of Nonoperative Management of Ileocolic Intussusception in Children. Euroasian J Hepato-Gastroenterol 2024;14(1):81-85.

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儿童回结肠肠套叠非手术治疗失败预测因素研究
背景:在发展中国家,手术仍是治疗肠套叠的主要方法。尽管高收入国家已转向非手术治疗,但相应的肠切除率仍然很高。我们的目的是研究来我院就诊的肠套叠患者的临床概况,并评估肠套叠非手术治疗成功或失败的临床和放射学预测因素:这项前瞻性研究在小儿外科进行,历时3年,共纳入了118名到我院急诊科就诊的肠套叠患者,这些患者均具有肠套叠的特征,并接受了相应的治疗,包括静水压减压或手术治疗:我们发现大多数患者为男性(65.5%)。平均年龄为 13.54 个月。间歇性疼痛是最常见的症状。疼痛和呕吐均不影响预后。白细胞总数(TLC)、C反应蛋白(CRP)和乳酸水平升高等实验室参数与静水压降低失败有显著相关性。X光检查发现有空气积液的患者更有可能接受手术治疗。超声检查发现肠壁水肿、肠道蠕动襻和病理性导尿点也与静水压减容失败有关。水压减容术的总体成功率为 85.5%:结论:肠套叠静水压减容术是治疗肠套叠的一种安全有效的方法。可能降低其成功几率的因素包括持续疼痛、烦躁、触痛、TLC、CRP 和乳酸盐水平等实验室指标失常、X 光片上的气液水平、肠壁水肿、肠蠕动和导尿点的存在:儿童回结肠肠套叠非手术治疗失败的预测因素研究。Euroasian J Hepato-Gastroenterol 2024;14(1):81-85.
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