Willingness to pay for expanded non-invasive prenatal screening - An online discrete choice experiment from the perspective of women living in Western Australia.

IF 1.4 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
Sarah Long, Peter O'Leary, Richard Norman, Jan E Dickinson
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引用次数: 0

Abstract

Introduction: Ongoing advances in genetic technology may soon provide prenatal screening for multiple genetic conditions.

Aims: The aims were to investigate what prenatal screening test characteristics women prioritise and their willingness to pay for these tests.

Methods: We designed an online survey incorporating a series of discrete choice scenarios. Dimensions and levels were selected based on existing prenatal tests and a hypothetical prenatal test that could non-invasively detect multiple genetic disorders in pregnancy. Participants were recruited from social media platforms. Data were analysed using conditional logistic regression and latent class analysis (LCA).

Results: A total of 219 women completed the survey. Women with higher incomes and those with a tertiary education were willing to pay more than other groups. The maximum willingness to pay was AUD1870 (95% confidence interval: 1630, 2112) for a hypothetical non-invasive test to detect multiple genetic conditions in early pregnancy. An LCA demonstrated considerable heterogeneity in preferences, differing in both overall preference for testing and test characteristics considered most attractive. Among the participants, decision factors cited by 14.5% of participants were the risk of pregnancy loss, making them less likely to undergo testing; for 32.1% participants, accuracy was a major factor, and they were very likely to have testing; for 12.9%, test availability early in pregnancy was a decision factor.

Conclusions: If a non-invasive test that could detect the greatest number of genetic disorders in pregnancy was available, the priorities were test accuracy, risk of pregnancy loss and a test available early in pregnancy.

为扩大无创产前筛查付费的意愿--从西澳大利亚妇女的角度进行的在线离散选择实验。
导言:目的:本研究旨在调查妇女优先考虑的产前筛查测试特征以及她们愿意为这些测试付费的意愿:我们设计了一项在线调查,其中包含一系列离散选择情景。我们根据现有的产前检查和一种可无创伤检测妊娠期多种遗传疾病的假设产前检查来选择维度和水平。参与者是从社交媒体平台上招募的。数据采用条件逻辑回归和潜类分析(LCA)进行分析:共有 219 名妇女完成了调查。与其他群体相比,收入较高和受过高等教育的女性愿意支付更多费用。对于检测孕早期多种遗传病的假设无创检测,最高支付意愿为 1870 澳元(95% 置信区间:1630-2112)。一项 LCA 显示,受试者的偏好存在相当大的异质性,他们对检测的总体偏好和认为最有吸引力的检测特征都不尽相同。在参与者中,14.5% 的参与者提到的决定因素是妊娠损失的风险,这使他们不太可能接受检测;32.1% 的参与者认为准确性是一个主要因素,他们非常有可能接受检测;12.9% 的参与者认为在孕早期能否进行检测是一个决定因素:结论:如果有一种非侵入性检测方法可以检测出最多的妊娠遗传疾病,那么优先考虑的因素是检测的准确性、妊娠损失的风险和在妊娠早期进行检测。
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来源期刊
CiteScore
3.40
自引率
11.80%
发文量
165
审稿时长
4-8 weeks
期刊介绍: The Australian and New Zealand Journal of Obstetrics and Gynaecology (ANZJOG) is an editorially independent publication owned by the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) and the RANZCOG Research foundation. ANZJOG aims to provide a medium for the publication of original contributions to clinical practice and/or research in all fields of obstetrics and gynaecology and related disciplines. Articles are peer reviewed by clinicians or researchers expert in the field of the submitted work. From time to time the journal will also publish printed abstracts from the RANZCOG Annual Scientific Meeting and meetings of relevant special interest groups, where the accepted abstracts have undergone the journals peer review acceptance process.
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