Mechanisms of Mycobacterium tuberculosis Drug Resistance

Pub Date : 2024-07-09 DOI:10.3103/s0891416824700010
M. V. Shulgina
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Abstract

The review presents the results of investigations of the mechanisms of action of long-used and new antituberculosis drugs, and information about new chemical compounds as potential antituberculosis drugs. Data are given on mutations in a number of infectant genes associated with or leading to bacterial resistance to these drugs. The review comprises the results of 67 publications, systematic reviews, and electronic databases.

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结核分枝杆菌的抗药性机制
摘要 本综述介绍了对长期使用的抗结核药物和新型抗结核药物作用机制的研究结果,以及有关新型化合物作为潜在抗结核药物的信息。文中还提供了与细菌耐药性有关或导致细菌耐药性的一些感染基因突变的数据。本综述包括 67 篇出版物、系统综述和电子数据库的成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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