CFIFusion: Dual-Branch Complementary Feature Injection Network for Medical Image Fusion

IF 3 4区 计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Yiyuan Xie, Lei Yu, Cheng Ding
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Abstract

The goal of fusing medical images is to integrate the diverse information that multimodal medical images hold. However, the challenges lie in the limitations of imaging sensors and the issue of incomplete modal information retention, which make it difficult to produce images encompassing both functional and anatomical information. To overcome these obstacles, several medical image fusion techniques based on CNN or transformer architectures have been presented. Nevertheless, CNN technique struggles to establish extensive dependencies between the fused and source images, and transformer architecture often overlooks shallow complementary features. To augment both the feature extraction capacity and the stability of the model, we introduce a framework, called dual-branch complementary feature injection fusion (CFIFusion) technique, a for multimodal medical image fusion framework that combines unsupervised models of CNN model and transformer techniques. Specifically, in our framework, the entire source image and segmented source image are input into an adaptive backbone network to learn global and local features, respectively. To further retain the source images' complementary information, we design a multi-scale complementary feature extraction framework as an auxiliary module, focusing on calculating feature differences at each level to capture the shallow complementary information. Then, we design a shallow information preservation module tailored for sliced image characteristics. Experimental results on the Harvard whole brain atlas dataset demonstrate that CFIFusion shows greater benefits than recent state-of-the-art algorithms in terms of both subjective and objective evaluations.

CFIFusion:用于医学图像融合的双分支互补特征注入网络
融合医学图像的目标是整合多模态医学图像所包含的各种信息。然而,所面临的挑战在于成像传感器的局限性和模态信息保留不完整的问题,因此很难生成同时包含功能和解剖信息的图像。为了克服这些障碍,人们提出了几种基于 CNN 或变压器架构的医学图像融合技术。然而,CNN 技术难以在融合图像和源图像之间建立广泛的依赖关系,而变换器架构往往会忽略浅层互补特征。为了增强特征提取能力和模型的稳定性,我们引入了一种名为双分支互补特征注入融合(CFIFusion)技术的框架,这是一种结合了 CNN 模型和变换器技术的无监督模型的多模态医学图像融合框架。具体来说,在我们的框架中,整个源图像和分割后的源图像被输入自适应骨干网络,分别学习全局和局部特征。为了进一步保留源图像的互补信息,我们设计了一个多尺度互补特征提取框架作为辅助模块,重点计算各层次的特征差异,以捕捉浅层互补信息。然后,我们设计了针对切片图像特征的浅层信息保存模块。在哈佛大学全脑图集上的实验结果表明,CFIFusion 在主观和客观评价方面都比最近最先进的算法更有优势。
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来源期刊
International Journal of Imaging Systems and Technology
International Journal of Imaging Systems and Technology 工程技术-成像科学与照相技术
CiteScore
6.90
自引率
6.10%
发文量
138
审稿时长
3 months
期刊介绍: The International Journal of Imaging Systems and Technology (IMA) is a forum for the exchange of ideas and results relevant to imaging systems, including imaging physics and informatics. The journal covers all imaging modalities in humans and animals. IMA accepts technically sound and scientifically rigorous research in the interdisciplinary field of imaging, including relevant algorithmic research and hardware and software development, and their applications relevant to medical research. The journal provides a platform to publish original research in structural and functional imaging. The journal is also open to imaging studies of the human body and on animals that describe novel diagnostic imaging and analyses methods. Technical, theoretical, and clinical research in both normal and clinical populations is encouraged. Submissions describing methods, software, databases, replication studies as well as negative results are also considered. The scope of the journal includes, but is not limited to, the following in the context of biomedical research: Imaging and neuro-imaging modalities: structural MRI, functional MRI, PET, SPECT, CT, ultrasound, EEG, MEG, NIRS etc.; Neuromodulation and brain stimulation techniques such as TMS and tDCS; Software and hardware for imaging, especially related to human and animal health; Image segmentation in normal and clinical populations; Pattern analysis and classification using machine learning techniques; Computational modeling and analysis; Brain connectivity and connectomics; Systems-level characterization of brain function; Neural networks and neurorobotics; Computer vision, based on human/animal physiology; Brain-computer interface (BCI) technology; Big data, databasing and data mining.
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