Effects of Preoperative Oral Carbohydrates on Recovery After Laparoscopic Cholecystectomy: A Meta-analysis of Randomized Controlled Trials

IF 1.6 4区医学 Q2 NURSING

Journal of Perianesthesia Nursing Pub Date : 2025-02-01 DOI:10.1016/j.jopan.2024.03.007

Xiao-Han Wang MM , Ze-Yang Wang MM , Zheng-Ru Shan MM , Rui Wang MM , Zhi-Ping Wang PhD

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引用次数: 0

Abstract

Purpose

The objective of this meta-analysis was to evaluate the efficacy of administering preoperative oral carbohydrates (CHO) compared to a control treatment in improving postoperative recovery outcomes for patients undergoing laparoscopic cholecystectomy (LC).

Design

A meta-analysis of randomized controlled trials.

Methods

Through systematic searches in PubMed, Embase, and the Cochrane Library, randomized controlled trials focusing on preoperative oral carbohydrates for patients undergoing LC were collected. Data analysis was conducted using the Revman 5.3 software.

Findings

The meta-analysis incorporated 19 randomized studies, with a total of 1,568 participants. Meta-analysis results indicated that patients receiving CHO reported notably lower postoperative pain compared to those fasting (P = .006) or on placebo (P = .003). Furthermore, a significant reduction in preoperative hunger was observed in the CHO group compared to the controls (P = .002). A notable difference was also identified in the postoperative Homeostasis Model Assessment-IR changes between the CHO and control groups (P = .02). No significant variations were observed in thirst, postoperative nausea and vomiting, insulin level alterations, glucose level changes, duration of hospital stay, or recovery quality.

Conclusions

Preoperative oral carbohydrates may alleviate hunger and pain, and attenuate postoperative insulin resistance more effectively than either overnight fasting or placebo in patients undergoing LC.

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术前口服碳水化合物对腹腔镜胆囊切除术后恢复的影响：随机对照试验的 Meta 分析。

目的：本荟萃分析旨在评估与对照组相比，术前口服碳水化合物（CHO）对改善腹腔镜胆囊切除术（LC）患者术后恢复效果的有效性：对随机对照试验进行荟萃分析：方法：通过在 PubMed、Embase 和 Cochrane 图书馆进行系统检索，收集了针对接受腹腔镜胆囊切除术的患者术前口服碳水化合物的随机对照试验。数据分析使用 Revman 5.3 软件进行：荟萃分析纳入了 19 项随机研究，共有 1,568 名参与者。荟萃分析结果表明，与禁食（P = .006）或服用安慰剂（P = .003）的患者相比，服用 CHO 的患者术后疼痛明显减轻。此外，与对照组相比，CHO 组患者术前饥饿感明显减少（P = .002）。CHO 组和对照组的术后体内平衡模型评估--红外线变化也有明显差异（P = .02）。在口渴、术后恶心和呕吐、胰岛素水平变化、血糖水平变化、住院时间或恢复质量方面未观察到明显差异：结论：对于接受腹腔镜手术的患者来说，术前口服碳水化合物可减轻饥饿感和疼痛，并比隔夜禁食或安慰剂更有效地减轻术后胰岛素抵抗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perianesthesia Nursing NURSING-

CiteScore

2.20

自引率

17.60%

发文量

279

审稿时长

90 days

期刊介绍： The Journal of PeriAnesthesia Nursing provides original, peer-reviewed research for a primary audience that includes nurses in perianesthesia settings, including ambulatory surgery, preadmission testing, postanesthesia care (Phases I and II), extended observation, and pain management. The Journal provides a forum for sharing professional knowledge and experience relating to management, ethics, legislation, research, and other aspects of perianesthesia nursing.