Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees.

IF 3.4 3区 医学 Q2 GERIATRICS & GERONTOLOGY
Drugs & Aging Pub Date : 2024-07-01 Epub Date: 2024-07-09 DOI:10.1007/s40266-024-01124-x
Tasce Bongiovanni, Siqi Gan, Emily Finlayson, Joseph S Ross, James D Harrison, John Boscardin, Michael A Steinman
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引用次数: 0

Abstract

Background: Surgeons have come under increased scrutiny for postoperative pain management, particularly for opioid prescribing. To decrease opioid use but still provide pain control, nonopioid medications such as muscle relaxants are being used, which can be harmful in older adults. However, the prevalence of muscle relaxant prescribing, trends in use over time, and risk of prolonged use are unknown.

Study design: Using a 20% representative Medicare sample, we conducted a retrospective analysis of muscle relaxant prescribing to patients ≥ 65 years of age. We merged patient data from Medicare Carrier, MedPAR, and Outpatient Files with Medicare Part D for the years 2013-2018. A total of 14 surgical procedures were included to represent a wide range of anatomic regions and specialties.

Results: The study cohort included 543,929 patients. Of the cohort, 8111 (1.5%) received a new muscle relaxant prescription at discharge. Spine procedures accounted for 12% of all procedures but 56% of postoperative prescribing. Overall, the rate of prescribing increased over the time period (1.4-2.0%, p < 0.001), with increases in prescribing primarily in the spine (7-9.6%, p < 0.0001) and orthopedic procedure groups (0.9-1.4%, p < 0.0001). Of patients discharged with a new muscle relaxant prescription, 10.7% had prolonged use.

Conclusions: The use of muscle relaxants in the postoperative period for older adults is low, but increasing over time, especially in ortho and spine procedures. While pain control after surgery is crucial, surgeons should carefully consider the risks of muscle relaxant use, especially for older adults who are at higher risk for medication-related problems.

Abstract Image

传统医疗保险 D 部分参保者手术后使用肌肉松弛剂的情况。
背景:外科医生在术后疼痛管理,尤其是阿片类药物处方方面受到越来越多的审查。为了减少阿片类药物的使用但仍能控制疼痛,目前正在使用肌肉松弛剂等非阿片类药物,但这些药物对老年人可能有害。然而,肌肉松弛剂处方的普遍性、随时间推移的使用趋势以及长期使用的风险尚不清楚:研究设计:我们利用具有 20% 代表性的医疗保险样本,对年龄≥ 65 岁的患者肌肉松弛剂处方进行了回顾性分析。我们合并了 2013-2018 年医疗保险承保人、MedPAR、门诊病人档案和医疗保险 D 部分的病人数据。共纳入了 14 种外科手术,以代表广泛的解剖区域和专科:研究队列包括 543929 名患者。其中,8111 人(1.5%)在出院时收到了新的肌肉松弛剂处方。脊柱手术占所有手术的 12%,但占术后处方的 56%。总体而言,处方率在这段时间内有所上升(1.4-2.0%,p < 0.001),处方率上升主要集中在脊柱手术组(7-9.6%,p < 0.0001)和骨科手术组(0.9-1.4%,p < 0.0001)。在开具新的肌肉松弛剂处方出院的患者中,10.7%的患者长期使用肌肉松弛剂:结论:老年人术后使用肌肉松弛剂的比例较低,但随着时间的推移在不断增加,尤其是在骨科和脊柱手术中。虽然术后疼痛控制至关重要,但外科医生应仔细考虑使用肌肉松弛剂的风险,尤其是对那些出现药物相关问题风险较高的老年人。
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来源期刊
Drugs & Aging
Drugs & Aging 医学-老年医学
CiteScore
5.50
自引率
7.10%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Drugs & Aging delivers essential information on the most important aspects of drug therapy to professionals involved in the care of the elderly. The journal addresses in a timely way the major issues relating to drug therapy in older adults including: the management of specific diseases, particularly those associated with aging, age-related physiological changes impacting drug therapy, drug utilization and prescribing in the elderly, polypharmacy and drug interactions.
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