MAGNITUDE OF NEONATAL HYPOGLYCEMIA AND ITS ASSOCIATED FACTORS AMONG NEONATES ADMITTED TO NEONATAL INTENSIVE CARE UNIT AT HAWASSA CITY PUBLIC HOSPITALS, ETHIOPIA, 2023.

selam tadele, wegene jembere, Mastewal Aschale, Tewodros Mulugeta, Samuel Jigso, Mequanint Ayehu, Migbar Sibhat
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Abstract

Abstract Background: Neonatal hypoglycemia is one of the most common metabolic abnormalities seen in newborns. It is a major contributing factor to neonatal morbidity and mortality. Globally, it affects around 5–15% of all babies and approximately 50% of at-risk babies.. In Ethiopia, neonatal hypoglycemia is frequently diagnosed and one of the commonest causes of admission to the neonatal intensive care unit. Nevertheless, documented records regarding its magnitude and factors associated with hypoglycemia are scarce in the study area. Therefore we aimed to assess the magnitude of neonatal hypoglycemia and its associated factors among neonates admitted to the neonatal intensive care unit at Hawassa City Public Hospitals, Ethiopia. Method: Institution-based cross-sectional study was conducted from April 20 – June 20, 2023among 293 neonates. A systematic random sampling technique was used to reach the study subjects. The data was collected through face-to-face interviews and card review by using structured pretested questionnaire and analyzed using SPSS software version 25. A multivariable logistic regression model was used to determine factors significantly associated with neonatal hypoglycemia with adjusted odds ratio, p-values <0.05 at 95% confidence interval (CI). Result: The magnitude of neonatal hypoglycemia was found 16.6%. Variables significantly associated with the occurrence of neonatal hypoglycemia were: Diabetes mellitus [AOR=9.8, 95%CI (3.08-31.37)], perinatal asphyxia [AOR=2.87, 95%CI (1.07-7.72)], delayed initiation of breastfeeding [AOR=2.63, 95%CI (1.04-6.6)] and hypothermia [AOR=3.8, 95%CI (1.6-9.1)]. Conclusion: In this study the magnitude of neonatal hypoglycemia among neonates was high. Neonates with hypothermia, perinatal asphyxia, and delayed initiation of breastfeeding and maternal history of diabetes mellitus have an increased risk of developing hypoglycemia. Hence, Health care providers who are working on delivery and neonatal care should focus on early identification and management of these identified factors.
2023 年埃塞俄比亚哈瓦萨市公立医院新生儿重症监护室收治的新生儿低血糖症的严重程度及其相关因素。
摘要 背景:新生儿低血糖是新生儿最常见的代谢异常之一。它是导致新生儿发病和死亡的一个主要因素。在全球范围内,约有 5-15% 的新生儿和约 50% 的高危新生儿受到低血糖的影响。在埃塞俄比亚,新生儿低血糖症经常被诊断出来,也是新生儿重症监护室最常见的病因之一。然而,在研究地区,有关新生儿低血糖症的严重程度和相关因素的记录却很少。因此,我们旨在评估埃塞俄比亚哈瓦萨市公立医院新生儿重症监护室收治的新生儿低血糖的严重程度及其相关因素:方法:于 2023 年 4 月 20 日至 6 月 20 日对 293 名新生儿进行了基于医院的横断面研究。研究采用了系统随机抽样技术。数据收集采用面对面访谈和卡片审查的方式,使用预先测试的结构化问卷,并使用 SPSS 软件 25 版进行分析。采用多变量逻辑回归模型确定与新生儿低血糖显著相关的因素,调整后的几率比为0.05,95%置信区间(CI)为0.05:结果:新生儿低血糖发生率为 16.6%。与新生儿低血糖显著相关的变量有糖尿病[AOR=9.8,95%CI (3.08-31.37)]、围产期窒息[AOR=2.87,95%CI (1.07-7.72)]、开始母乳喂养延迟[AOR=2.63,95%CI (1.04-6.6)]和体温过低[AOR=3.8,95%CI (1.6-9.1)]:在这项研究中,新生儿低血糖的发生率很高。新生儿体温过低、围产期窒息、开始母乳喂养时间延迟以及母亲有糖尿病史,都会增加新生儿发生低血糖的风险。因此,从事分娩和新生儿护理的医护人员应重点关注早期识别和管理这些已发现的因素。
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