ImmRNA: a database of RNAs associated with tumor immunity.

IF 3.4 4区生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY

Database: The Journal of Biological Databases and Curation Pub Date : 2024-07-06 DOI:10.1093/database/baae052

Fangfang Shen, Zelian Li, Pengfei Wu, Jinpeng Wang

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引用次数: 0

Abstract

The relationship between different ribonucleic acids (RNAs) and tumor immunity has been widely investigated. However, a systematic description of tumor immune-related RNAs in different tumors is still lacking. We collected the relationship of tumor immune-related RNAs from the published literature and presented them in a user-friendly interface, "ImmRNA" (http://www.immrna.cn/), to provide a resource to study immune-RNA-cancer regulatory relations. The ImmRNA contains 49 996 curated entries. Each entry includes gene symbols, gene types, target genes, downstream effects, functions, immune cells, and other information. By rearranging and reanalyzing the data, our dataset contains the following key points: (i) providing the links between RNAs and the immune in cancers, (ii) displaying the downstream effects and functions of RNAs, (iii) listing immune cells and immune pathways related to RNA function, (iv) showing the relationship between RNAs and prognostic outcomes, and (v) exhibiting the experimental methods described in the article. ImmRNA provides a valuable resource for understanding the functions of tumor immune-related RNAs. Database URL: http://www.immrna.cn/.

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ImmRNA：与肿瘤免疫相关的 RNA 数据库。

不同核糖核酸（RNA）与肿瘤免疫之间的关系已被广泛研究。然而，目前仍缺乏对不同肿瘤中肿瘤免疫相关 RNA 的系统描述。我们从已发表的文献中收集了肿瘤免疫相关RNA的关系，并将其呈现在一个用户友好的界面 "ImmRNA"（http://www.immrna.cn/）中，为研究免疫-RNA-癌症调控关系提供了一个资源库。ImmRNA包含49 996个策划条目。每个条目包括基因符号、基因类型、靶基因、下游效应、功能、免疫细胞等信息。通过重新整理和分析数据，我们的数据集包含以下要点：(i) 提供癌症中 RNA 与免疫之间的联系；(ii) 显示 RNA 的下游效应和功能；(iii) 列出与 RNA 功能相关的免疫细胞和免疫途径；(iv) 显示 RNA 与预后结果之间的关系；(v) 展示文章中描述的实验方法。ImmRNA 为了解肿瘤免疫相关 RNA 的功能提供了宝贵的资源。数据库网址：http://www.immrna.cn/。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Database: The Journal of Biological Databases and Curation MATHEMATICAL & COMPUTATIONAL BIOLOGY-

CiteScore

9.00

自引率

3.40%

发文量

100

审稿时长

>12 weeks

期刊介绍： Huge volumes of primary data are archived in numerous open-access databases, and with new generation technologies becoming more common in laboratories, large datasets will become even more prevalent. The archiving, curation, analysis and interpretation of all of these data are a challenge. Database development and biocuration are at the forefront of the endeavor to make sense of this mounting deluge of data. Database: The Journal of Biological Databases and Curation provides an open access platform for the presentation of novel ideas in database research and biocuration, and aims to help strengthen the bridge between database developers, curators, and users.