Hair Shaft Abnormalities as a Dermoscopic Feature of Mycosis Fungoides: Pilot Results.

IF 3.5 3区医学 Q1 DERMATOLOGY

Dermatology and Therapy Pub Date : 2024-08-01 Epub Date: 2024-07-03 DOI:10.1007/s13555-024-01206-z

Magdalena Jasińska, Joanna Czuwara, Nino Lortkipanidze, Agnieszka Michalczyk, Barbara Borkowska, Patrycja Gajda-Mróz, Marta Kurzeja, Małgorzata Olszewska, Lidia Rudnicka, Adriana Rakowska

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引用次数: 0

Abstract

Introduction: Diagnosis of persistent erythematous, scaly patches, or plaques can be complex since psoriasis (Ps), eczematous dermatitis (ED), and mycosis fungoides (MF) can be considered. Dermoscopy, which is a noninvasive diagnostic tool, is commonly used to examine blood vessels, scales, and background color; however, research on hair shaft evaluation in inflammatory dermatoses remains scarce. The aim of the study was dermoscopic evaluation of hair shafts in skin lesions localized on the non-scalp skin areas in patients diagnosed with MF, Ps, and ED.

Methods: This was a retrospective evaluation of 55 patients diagnosed with MF, Ps, and ED. Photographic and dermoscopic documentation of these patients and detailed medical history were evaluated.

Results: A total of 21 patients with MF, 21 patients with Ps, and 13 patients with ED were evaluated. The examination revealed the presence of various abnormalities of hair shafts (e.g., numerous pili torti, single pili torti, 8-shaped hairs, pigtail hairs, broken hairs, hair shafts rapidly tapered over long sections, hair shafts irregular in thickness, angulated hairs, branched hairs, the presence of trichorrhexis nodosa, and monilethrix-like hairs), yellow dots, and black dots. The presence of pili torti was found in 80% of patients with MF, compared with 16% of patients with Ps and 8% of patients with ED (p < 0.005), with multiple pili torti found only in MF patients (67%) (p < 0.005). Statistically significant differences also applied to hair shafts rapidly tapering over long sections and 8-shaped hairs, which occurred only in MF patients (p < 0.005 and p = 0.035, respectively).

Conclusions: The presence of hair shaft abnormalities such as numerous pili torti, 8-shaped hairs, and hair shafts rapidly tapering over long sections is an important criterion that should be considered in the dermoscopic differentiation of the patchy/plaque mycosis fungoides and inflammatory dermatoses, such as psoriasis and eczematous dermatitis localized on the non-scalp skin areas.

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作为真菌病皮肤镜特征的发轴异常：试验结果

简介：由于银屑病（Ps）、湿疹性皮炎（ED）和霉菌性真菌病（MF）都可能被考虑在内，因此对顽固性红斑、鳞屑性斑块或斑块的诊断可能很复杂。皮肤镜是一种无创诊断工具，通常用于检查血管、鳞屑和背景颜色；然而，有关炎症性皮肤病中毛发轴评估的研究仍然很少。本研究的目的是通过皮肤镜评估被诊断为 MF、Ps 和 ED 患者非头皮部位皮损的毛干：这是对55名确诊为MF、Ps和ED患者的回顾性评估。对这些患者的照片和皮肤镜记录以及详细的病史进行了评估：共评估了 21 名 MF 患者、21 名 Ps 患者和 13 名 ED 患者。检查结果显示，患者的毛干存在各种异常（如大量绒毛、单个绒毛、8 字形毛发、辫子状毛发、断裂的毛发、毛干在长段上迅速变细、毛干粗细不规则、成角的毛发、分枝的毛发、存在结节性毛发和单绒毛）、黄点和黑点。在 80% 的 MF 患者中发现有毛嚢，而在 Ps 患者中仅有 16%，在 ED 患者中仅有 8%（P 结论）：在皮肤镜下鉴别斑片状/斑块状真菌病和炎症性皮肤病（如局部非头皮部位的银屑病和湿疹性皮炎）时，毛干异常（如大量绒毛、8 字形毛发和毛干在长段上迅速变细）是一个重要标准。

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来源期刊

Dermatology and Therapy Medicine-Dermatology

CiteScore

6.00

自引率

8.80%

发文量

187

审稿时长

6 weeks

期刊介绍： Dermatology and Therapy is an international, open access, peer-reviewed, rapid publication journal (peer review in 2 weeks, published 3–4 weeks from acceptance). The journal is dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of dermatological therapies. Studies relating to diagnosis, pharmacoeconomics, public health and epidemiology, quality of life, and patient care, management, and education are also encouraged. Areas of focus include, but are not limited to all clinical aspects of dermatology, such as skin pharmacology; skin development and aging; prevention, diagnosis, and management of skin disorders and melanomas; research into dermal structures and pathology; and all areas of aesthetic dermatology, including skin maintenance, dermatological surgery, and lasers. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/case series, trial protocols, and short communications. Dermatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an International and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of quality research, which may be considered of insufficient interest by other journals. The journal appeals to a global audience and receives submissions from all over the world.