Research Progress in the Relationship between Intestinal Flora and Diabetes Mellitus.

Yingji Lai, Xianfeng Huang, Hongwei Sun, Qi Hui, Shanshan Hu
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Abstract

Diabetes mellitus is a common chronic metabolic disease characterized by a high incidence and disability rate. Intestinal flora refers to the microbial community that lives in the intestines and plays a crucial role in maintaining intestinal health and the human immune system. In recent years, an increasing body of research has revealed a close relationship between intestinal flora and diabetes. The pathophysiological mechanisms between them have also been constantly uncovered, and the regulation of intestinal flora has shown promising efficacy in the adjuvant treatment of diabetes. This study mainly summarized the characteristics and mechanisms of intestinal flora in patients with diabetes in recent years, as well as the methods of regulating intestinal flora to prevent and treat diabetes, and prospected the future research direction. This will offer a theoretical basis for the clinical adjuvant treatment of diabetes with intestinal flora and the development of new drugs.

肠道菌群与糖尿病关系的研究进展。
糖尿病是一种常见的慢性代谢性疾病,发病率和致残率都很高。肠道菌群是指生活在肠道中的微生物群落,在维护肠道健康和人体免疫系统方面发挥着至关重要的作用。近年来,越来越多的研究揭示了肠道菌群与糖尿病之间的密切关系。二者之间的病理生理机制也不断被揭示,肠道菌群的调节在糖尿病的辅助治疗中显示出良好的疗效。本研究主要总结了近年来糖尿病患者肠道菌群的特点和机制,以及调节肠道菌群预防和治疗糖尿病的方法,并展望了未来的研究方向。这将为肠道菌群辅助治疗糖尿病的临床研究和新药研发提供理论依据。
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