Gender Differences in Perceptions of Psoriatic Arthritis Disease Impact, Management, and Physician Interactions: Results from a Global Patient Survey.

IF 2.9 3区医学 Q2 RHEUMATOLOGY

Rheumatology and Therapy Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI:10.1007/s40744-024-00678-x

Lihi Eder, Pascal Richette, Laura C Coates, Valderilio F Azevedo, Joseph C Cappelleri, Edward P Johnson, Megan Hoang, Jade Moser, Meriem Kessouri

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引用次数: 0

Abstract

Introduction: We evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and patient-healthcare professional (HCP) interactions from the perspectives of patients with psoriatic arthritis (PsA).

Methods: Data were collected from a global online patient survey conducted by The Harris Poll (November 2, 2017 to March 12, 2018). Eligible patients were aged ≥ 18 years, with a self-reported diagnosis of PsA for > 1 year, had visited a rheumatologist/dermatologist in the past 12 months, and had reported previously using ≥ 1 conventional synthetic or biologic disease-modifying antirheumatic drug. Data were stratified by gender and analyzed descriptively, inferentially by binomial (chi-square) tests, and by multivariate logistic regression models.

Results: Data from 1286 patients who participated were included: 52% were female, 48% were male. Varying perceptions of disease severity between males and females were indicated by differences in symptoms leading to a diagnosis of PsA, and in symptoms reported despite treatment; more females than males reported joint tenderness, skin patches/plaques, and enthesitis. More females than males reported a major/moderate impact of PsA on their physical activity and emotional/mental well-being. Reasons for switching medication differed between genders, with more females switching because they perceived their medication to not be effective enough related to their joint symptoms. More females than males were very satisfied with their communication with their rheumatologist and were more likely to discuss the impact of PsA on their daily lives, their treatment satisfaction, and treatment goals with their rheumatologist.

Conclusions: Patients' perceptions of the impact of PsA on HRQoL, treatment management, and interactions with HCPs varied between males and females. More females than males reported major/moderate physical and emotional impacts of PsA. When treating patients, it is important for HCPs to consider the potential impact of gender on patients' experience of PsA and its symptoms. Graphical plain language summary available for this article.

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对银屑病关节炎疾病影响、管理和医生互动看法的性别差异：全球患者调查结果

导言：我们从银屑病关节炎（PsA）患者的角度评估了性别对疾病严重程度、健康相关生活质量（HRQoL）、治疗管理以及患者与医护人员（HCP）互动的影响：数据收集自哈里斯民意调查（The Harris Poll）进行的全球患者在线调查（2017 年 11 月 2 日至 2018 年 3 月 12 日）。符合条件的患者年龄≥18岁，自述诊断为PsA超过1年，在过去12个月内曾就诊于风湿免疫科/皮肤科医生，并自述曾使用过≥1种常规合成或生物改善病情抗风湿药物。数据按性别进行了分层，并进行了描述性分析、二项式（卡方检验）推断分析和多变量逻辑回归模型分析：结果：共纳入了 1286 名患者的数据：52%为女性，48%为男性。男性和女性对疾病严重程度的不同看法表现在导致诊断为PsA的症状和治疗后仍报告的症状上的差异；报告关节触痛、皮肤斑块/斑块和腱鞘炎的女性多于男性。报告 PsA 对其身体活动和情绪/心理健康造成重大/中度影响的女性多于男性。换药的原因因性别而异，更多女性换药的原因是她们认为药物对关节症状不够有效。与男性相比，更多女性对与风湿免疫科医生的沟通表示非常满意，并且更愿意与风湿免疫科医生讨论PsA对其日常生活的影响、治疗满意度以及治疗目标：患者对 PsA 对 HRQoL、治疗管理以及与 HCPs 互动的影响的看法在男性和女性之间存在差异。报告 PsA 对身体和情绪造成重大/中度影响的女性多于男性。在治疗患者时，保健医生必须考虑到性别对患者的 PsA 体验及其症状的潜在影响。本文有图形化简明语言摘要。

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来源期刊

Rheumatology and Therapy RHEUMATOLOGY-

CiteScore

6.00

自引率

5.30%

发文量

审稿时长

6 weeks

期刊介绍： Aims and Scope Rheumatology and Therapy is an international, open access, peer reviewed, rapid publication journal dedicated to the publication of high-quality clinical (all phases), observational, real-world and health outcomes research around the discovery, development, and use of rheumatologic therapies. Studies relating to diagnosis, pharmacoeconomics, public health, quality of life, and patient care, management, and education are also welcomed. Areas of focus include, but are not limited to, rheumatoid arthritis, gout, gouty arthritis, psoriatic arthritis, osteoarthritis, juvenile idiopathic/rheumatoid arthritis, systemic lupus erythematosus, axial spondyloarthritis, Pompe’s disease, inflammatory joint conditions, musculoskeletal conditions, systemic sclerosis, and fibromyalgia. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, case reports, trial protocols, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Rheumatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research. Ethics and Disclosures The journal is a member of the Committee on Publication Ethics (COPE) and subscribes to its principles on how to deal with acts of misconduct thereby committing to investigate allegations of misconduct in order to ensure the integrity of research. Content in this journal is peer-reviewed (Single-blind). For more information on our publishing ethics policies, please see here: https://www.springer.com/gp/editorial-policies Rapid Publication The journal’s rapid publication timelines aim for a peer review decision within 2 weeks of submission. If an article is accepted it will be published online 3-4 weeks from acceptance. These rapid timelines are achieved through the combination of a dedicated in-house editorial team, who closely manage article workflow, and an extensive Editorial and Advisory Board who assist with rapid peer review. This allows the journal to support the rapid dissemination of research, whilst still providing robust peer review. Combined with the journal’s open access model this allows for the rapid and efficient communication of the latest research and reviews, allowing the advancement of rheumatologic therapies. 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