Association Between Natural Hair Color, Race, and Alopecia.

IF 3.5 3区医学 Q1 DERMATOLOGY

Dermatology and Therapy Pub Date : 2024-08-01 Epub Date: 2024-07-02 DOI:10.1007/s13555-024-01218-9

Kanika Kamal, David Xiang, Katherine Young, David E Fisher, Arash Mostaghimi, Nicholas Theodosakis

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引用次数: 0

Abstract

Introduction: Limited epidemiologic data has suggested direct associations between hair pigment, race, and incidence of alopecia areata (AA). Here, we examine the relationship between natural hair color, race, and the lifetime risk alopecia.

Methods: In this case-control study, we included UK Biobank patients of all races and self-reported hair color with diagnoses of AA, androgenetic alopecia (AGA), or scarring alopecia (SA). Multivariable logistic regression was used to detect differences in lifetime risk.

Results: Findings reveal a significantly increased risk of AA among individuals with black hair compared to dark brown hair (OR 1.71 [95% CI 1.22-2.38], p < 0.001). Those with red or blonde hair showed a decreased risk of AA (0.74 [0.56-0.97]; 0.62 [0.41-0.95], p < 0.05). No racial differences in AA prevalence were observed among individuals with black hair.

Conclusions: Darker hair colors may be associated with a higher risk of AA, lighter hair colors with a lower risk, and differences in hair color could contribute to previously noted racial variations in AA incidence, potentially influencing dermatologists' perspectives on the disease's epidemiology.

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自然发色、种族与脱发之间的关系。

导言：有限的流行病学数据表明，头发色素、种族和斑秃（AA）发病率之间存在直接联系。在此，我们研究了自然发色、种族与终生脱发风险之间的关系：在这项病例对照研究中，我们纳入了英国生物数据库（UK Biobank）中被诊断为AA、雄激素性脱发（AGA）或疤痕性脱发（SA）的各种族和自报发色患者。多变量逻辑回归用于检测终生风险的差异：结果：研究结果表明，与深棕色头发相比，黑色头发的人患 AA 的风险明显增加（OR 1.71 [95% CI 1.22-2.38]，p 结论：深色头发可能与雄激素性脱发（AGA）或瘢痕性脱发（SA）有关：发色较深的人罹患 AA 的风险可能较高，发色较浅的人罹患 AA 的风险较低，发色的差异可能会导致之前注意到的 AA 发病率的种族差异，并可能影响皮肤科医生对该疾病流行病学的看法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatology and Therapy Medicine-Dermatology

CiteScore

6.00

自引率

8.80%

发文量

187

审稿时长

6 weeks

期刊介绍： Dermatology and Therapy is an international, open access, peer-reviewed, rapid publication journal (peer review in 2 weeks, published 3–4 weeks from acceptance). The journal is dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of dermatological therapies. Studies relating to diagnosis, pharmacoeconomics, public health and epidemiology, quality of life, and patient care, management, and education are also encouraged. Areas of focus include, but are not limited to all clinical aspects of dermatology, such as skin pharmacology; skin development and aging; prevention, diagnosis, and management of skin disorders and melanomas; research into dermal structures and pathology; and all areas of aesthetic dermatology, including skin maintenance, dermatological surgery, and lasers. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/case series, trial protocols, and short communications. Dermatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an International and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of quality research, which may be considered of insufficient interest by other journals. The journal appeals to a global audience and receives submissions from all over the world.