Pupillary constriction on stimulation of the parietal cortex-A novel finding.

IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY
Brin Freund, Dileep Nair, Juan Bulacio, Imad Najm, Kenneth Taylor, Ahsan N Moosa
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引用次数: 0

Abstract

Pupillary changes can be an important semiologic feature in focal epilepsy. Though the subcortical networks involving pupillomotor function have been described, cortical generators of pupillary dilation and constriction in humans are not well known. In this report, we describe a case of pupillary constriction occurring during seizures in a patient with drug resistant focal epilepsy. On stereoelectroencephalography, onset was noted within the posterior segment of the right intraparietal sulcus and direct cortical electrical stimulation of these electrode contacts reproduced pupillary constriction associated with habitual seizures. This is the first case report to describe ictal pupillary constriction during SEEG with confirmation of the cortical localization by direct cortical electrical stimulation. The posterior segment of the right intraparietal sulcus localization of pupillary constriction may aid in surgical evaluation patients with drug resistant focal epilepsy.

刺激顶叶皮层时瞳孔收缩--一项新发现
瞳孔变化是局灶性癫痫的一个重要特征。虽然涉及瞳孔运动功能的皮层下网络已被描述,但人类瞳孔扩张和收缩的皮层发生器还不太为人所知。在本报告中,我们描述了一例在癫痫发作期间发生瞳孔收缩的耐药性局灶性癫痫患者。立体脑电图显示,发病部位位于右侧顶内沟后段,直接对这些电极触点进行皮层电刺激可再现与习惯性癫痫发作相关的瞳孔收缩。这是首例描述 SEEG 期间发作性瞳孔收缩并通过直接皮质电刺激确认皮质定位的病例报告。右顶叶内沟后段瞳孔收缩的定位有助于对耐药局灶性癫痫患者进行手术评估。
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来源期刊
Epileptic Disorders
Epileptic Disorders 医学-临床神经学
CiteScore
4.10
自引率
8.70%
发文量
138
审稿时长
6-12 weeks
期刊介绍: Epileptic Disorders is the leading forum where all experts and medical studentswho wish to improve their understanding of epilepsy and related disorders can share practical experiences surrounding diagnosis and care, natural history, and management of seizures. Epileptic Disorders is the official E-journal of the International League Against Epilepsy for educational communication. As the journal celebrates its 20th anniversary, it will now be available only as an online version. Its mission is to create educational links between epileptologists and other health professionals in clinical practice and scientists or physicians in research-based institutions. This change is accompanied by an increase in the number of issues per year, from 4 to 6, to ensure regular diffusion of recently published material (high quality Review and Seminar in Epileptology papers; Original Research articles or Case reports of educational value; MultiMedia Teaching Material), to serve the global medical community that cares for those affected by epilepsy.
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