Milestones to optimize of transjugular intrahepatic portosystemic shunt technique as a method for the treatment of portal hypertension complications.

IF 2.5 Q2 GASTROENTEROLOGY & HEPATOLOGY
Dmitry Victorovich Garbuzenko
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Abstract

This editorial describes the milestones to optimize of transjugular intrahepatic portosystemic shunt (TIPS) technique, which have made it one of the main methods for the treatment of portal hypertension complications worldwide. Innovative ideas, subsequent experimental studies and preliminary experience of use in cirrhotic patients contributed to the introduction of TIPS into clinical practice. At the moment, the main achievement in optimize of TIPS technique is progress in the qualitative characteristics of stents. The transition from bare metal stents to extended polytetrafluoroethylene-covered stent grafts made it possible to significantly prevent shunt dysfunction. However, the question of its preferred diameter, which contributes to an optimal reduction of portal pressure without the risk of developing post-TIPS hepatic encephalopathy, remains relevant. Currently, hepatic encephalopathy is one of the most common complications of TIPS, significantly affecting its effectiveness and prognosis. Careful selection of patients based on cognitive indicators, nutritional status, assessment of liver function, etc., will reduce the incidence of post-TIPS hepatic encephalopathy and improve treatment results. Optimize of TIPS technique has significantly expanded the indications for its use and made it one of the main methods for the treatment of portal hypertension complications. At the same time, there are a number of limitations and unresolved issues that require further randomized controlled trials involving a large cohort of patients.

优化经颈静脉肝内门体分流术作为治疗门脉高压并发症方法的里程碑。
这篇社论介绍了经颈静脉肝内门体分流术(TIPS)技术优化的里程碑,该技术已成为全球治疗门静脉高压并发症的主要方法之一。创新理念、随后的实验研究以及在肝硬化患者中使用的初步经验促使 TIPS 进入临床实践。目前,优化 TIPS 技术的主要成就是支架质量特性的进步。从裸金属支架到加长型聚四氟乙烯覆盖支架移植物的过渡,使大大防止分流功能障碍成为可能。然而,支架的首选直径问题依然存在,即支架的直径应有助于最佳地降低门脉压力,同时又不会产生 TIPS 后肝性脑病的风险。目前,肝性脑病是 TIPS 最常见的并发症之一,严重影响其疗效和预后。根据认知指标、营养状况、肝功能评估等对患者进行仔细筛选,可降低 TIPS 术后肝性脑病的发生率,改善治疗效果。TIPS 技术的优化大大扩展了其适应症,使其成为治疗门静脉高压并发症的主要方法之一。与此同时,TIPS 还存在一些局限性和未解决的问题,需要进一步开展大规模患者群的随机对照试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
World Journal of Hepatology
World Journal of Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.10
自引率
4.20%
发文量
172
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