Importance of the gut microbiota in the gut-liver axis in normal and liver disease.

IF 2.5 Q2 GASTROENTEROLOGY & HEPATOLOGY
Stanislav Kotlyarov
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引用次数: 0

Abstract

The gut microbiota is of growing interest to clinicians and researchers. This is because there is a growing understanding that the gut microbiota performs many different functions, including involvement in metabolic and immune processes that are systemic in nature. The liver, with its important role in detoxifying and metabolizing products from the gut, is at the forefront of interactions with the gut microbiota. Many details of these interactions are not yet known to clinicians and researchers, but there is growing evidence that normal gut microbiota function is important for liver health. At the same time, factors affecting the gut microbiota, including nutrition or medications, may also have an effect through the gut-liver axis.

肠道微生物群在正常人和肝病患者的肠道-肝轴中的重要性。
肠道微生物群越来越受到临床医生和研究人员的关注。这是因为人们越来越认识到,肠道微生物群具有许多不同的功能,包括参与全身性的代谢和免疫过程。肝脏在解毒和代谢来自肠道的产物方面发挥着重要作用,是与肠道微生物群相互作用的最前沿。临床医生和研究人员尚未了解这些相互作用的许多细节,但越来越多的证据表明,正常的肠道微生物群功能对肝脏健康非常重要。同时,影响肠道微生物群的因素,包括营养或药物,也可能通过肠道-肝脏轴产生影响。
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来源期刊
World Journal of Hepatology
World Journal of Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.10
自引率
4.20%
发文量
172
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