Opportunistic use of lumbar computed tomography and magnetic resonance imaging for osteoporosis screening.

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Osteoporosis International Pub Date : 2024-09-01 Epub Date: 2024-06-28 DOI:10.1007/s00198-024-07164-8

Xingxiao Pu, Bailian Liu, Daxing Wang, Weiping Xiao, Chengwei Liu, Shao Gu, Chengkui Geng, Haifeng Li

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引用次数: 0

Abstract

Compared with the healthy patients, patients with osteoporosis had a lower Hounsfield unit (HU) value and a higher vertebral bone quality (VBQ) score. Both the HU value and VBQ score can simply distinguish patients with osteoporosis (OP), with a cutoff value of HU value < 97.06 and VBQ score > 3.08.

Introduction: The purpose of this study is to determine whether the opportunistic use of computed tomography (CT) or magnetic resonance imaging (MRI) is effective for identifying spine surgical patients with OP.

Methods: We retrospectively evaluated 109 lumbar spine surgery patients who received lumbar quantitative CT (QCT) and MRI. Using the area under the curve, the CT-based HU value and MRI-based VBQ score were calculated. Then, based on the QCT results, receiver operating characteristic (ROC) curves were constructed to determine the diagnostic performance of the HU value and VBQ score.

Results: The HU value was significantly lower in the OP group, and the VBQ score was significantly higher in the OP group. Using the area under the curve, the diagnostic performance of the HU value and VBQ score for OP were 0.959 and 0.880, respectively. The diagnostic threshold values determined with optimal sensitivity and specificity were an HU value of 97.06 and a VBQ score of 3.08.

Conclusion: Opportunistic use of CT and MRI can simply distinguish patients with OP, which are expected to be potential alternatives to T-score for the osteoporosis screening.

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在骨质疏松症筛查中择机使用腰椎计算机断层扫描和磁共振成像。

与健康患者相比，骨质疏松症患者的 Hounsfield 单位（HU）值较低，而椎骨质量（VBQ）评分较高。HU值和VBQ评分都能简单区分骨质疏松症（OP）患者，HU值的临界值为3.08：本研究的目的是确定择机使用计算机断层扫描（CT）或磁共振成像（MRI）是否能有效鉴别患有 OP 的脊柱手术患者：我们回顾性评估了109例接受腰椎定量CT（QCT）和MRI检查的腰椎手术患者。通过曲线下面积，计算出基于 CT 的 HU 值和基于 MRI 的 VBQ 评分。然后，根据 QCT 结果构建接收者操作特征曲线（ROC），以确定 HU 值和 VBQ 评分的诊断性能：结果：OP 组的 HU 值明显较低，而 OP 组的 VBQ 评分明显较高。根据曲线下面积，HU 值和 VBQ 评分对 OP 的诊断率分别为 0.959 和 0.880。最佳灵敏度和特异性的诊断阈值为 HU 值 97.06 和 VBQ 评分 3.08：有机会使用 CT 和 MRI 可以简单区分 OP 患者，有望成为骨质疏松症筛查中 T 评分的潜在替代方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Osteoporosis International 医学-内分泌学与代谢

CiteScore

8.10

自引率

10.00%

发文量

224

审稿时长

3 months

期刊介绍： An international multi-disciplinary journal which is a joint initiative between the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA, Osteoporosis International provides a forum for the communication and exchange of current ideas concerning the diagnosis, prevention, treatment and management of osteoporosis and other metabolic bone diseases. It publishes: original papers - reporting progress and results in all areas of osteoporosis and its related fields; review articles - reflecting the present state of knowledge in special areas of summarizing limited themes in which discussion has led to clearly defined conclusions; educational articles - giving information on the progress of a topic of particular interest; case reports - of uncommon or interesting presentations of the condition. While focusing on clinical research, the Journal will also accept submissions on more basic aspects of research, where they are considered by the editors to be relevant to the human disease spectrum.