[Magnetic induced phase shift detection system based on a novel sensor for cerebral hemorrhage].

Q4 Medicine
Jie Liu, Lian Yan, Mingxin Qin, Haisheng Zhang, Mingsheng Chen
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引用次数: 0

Abstract

The main magnetic field, generated by the excitation coil of the magnetic induction phase shift technology detection system, is mostly dispersed field with small field strength, and the offset effect needs to be further improved, which makes the detection signal weak and the detection system difficult to achieve quantitative detection, thus the technology is rarely used in vivo experiments and clinical trials. In order to improve problems mentioned above, a new Helmholtz birdcage sensor was designed. Stimulation experiment was carried out to analyze the main magnetic field in aspects of intensity and magnetic distribution, then different bleeding volume and bleeding rates experiments were conducted to compared with traditional sensors. The results showed that magnetic field intensity in detection region was 2.5 times than that of traditional sensors, cancellation effect of the main magnetic field was achieved, the mean value of phase difference of 10 mL rabbit blood was (-3.34 ± 0.21)°, and exponential fitting adjusted R 2 between phase difference and bleeding volumes and bleeding rates were both 0.99. The proposed Helmholtz birdcage sensor has a uniform magnetic field with a higher field strength, enable more accurate quantification of hemorrhage and monitored change of bleeding rates, providing significance in magnetic induced technology research for cerebral hemorrhage detection.

[基于新型传感器的脑出血磁感应相移检测系统]。
磁感应相移技术检测系统的励磁线圈产生的主磁场多为分散磁场,场强较小,偏移效果有待进一步提高,检测信号较弱,检测系统难以实现定量检测,因此该技术在体内实验和临床试验中应用较少。为了改善上述问题,我们设计了一种新型亥姆霍兹鸟笼传感器。通过刺激实验分析了主磁场的强度和磁场分布,然后进行了不同出血量和出血率的实验,并与传统传感器进行了比较。结果表明,检测区域的磁场强度是传统传感器的 2.5 倍,达到了主磁场的抵消效果,10 mL 兔血的相位差平均值为(-3.34 ± 0.21)°,相位差与出血量和出血率之间的指数拟合调整 R 2 均为 0.99。所提出的亥姆霍兹鸟笼传感器磁场均匀,场强较高,能更准确地量化出血量和监测出血率的变化,为脑出血检测的磁诱导技术研究提供了重要依据。
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来源期刊
生物医学工程学杂志
生物医学工程学杂志 Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
4868
期刊介绍:
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