[Design and performance study of bone trabecular scaffolds based on triply periodic minimal surface method].

Q4 Medicine
Yutao Men, Shaocan Tang, Wei Chen, Fulong Liu, Chunqiu Zhang
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引用次数: 0

Abstract

Triply periodic minimal surface (TPMS) is widely used because it can be used to control the shape of porous scaffolds precisely by formula. In this paper, an I-wrapped package (I-WP) type porous scaffolds were constructed. The finite element method was used to study the relationship between the wall thickness and period, the morphology and mechanical properties of the scaffolds, as well as to study the compression and fluid properties. It was found that the porosity of I-WP type scaffolds with different wall thicknesses (0.1 ~ 0.2 mm) and periods (I-WP 1 ~ I-WP 5) ranged from 68.01% ~ 96.48%, and the equivalent elastic modulus ranged from 0.655 ~ 18.602 GPa; the stress distribution of the scaffolds tended to be uniform with the increase of periods and wall thicknesses; the equivalent elastic modulus of the I-WP type scaffolds was basically unchanged after the topology optimization, and the permeability was improved by 52.3%. In conclusion, for the I-WP type scaffolds, the period parameter can be adjusted first, then the wall thickness parameter can be controlled. Topology optimization can be combined to meet the design requirements. The I-WP scaffolds constructed in this paper have good mechanical properties and meet the requirements of repairing human bone tissue, which may provide a new choice for the design of artificial bone trabecular scaffolds.

[基于三周期最小面法的骨小梁支架设计与性能研究]。
三周期最小表面(TPMS)可以通过公式精确控制多孔支架的形状,因此被广泛应用。本文构建了一种 I 包裹(I-WP)型多孔支架。采用有限元法研究了支架的壁厚与周期、形态和力学性能之间的关系,并研究了支架的压缩性能和流体性能。研究发现,不同壁厚(0.1 ~ 0.2 mm)和周期(I-WP 1 ~ I-WP 5)的 I-WP 型支架的孔隙率范围为 68.01% ~ 96.48%,等效弹性模量范围为 0.655 ~ 18.602 GPa;随着周期和壁厚的增加,支架的应力分布趋于均匀;拓扑优化后,I-WP 型支架的等效弹性模量基本不变,透气性提高了 52.3%。总之,对于 I-WP 型脚手架,可以先调整周期参数,然后控制壁厚参数。可结合拓扑优化来满足设计要求。本文构建的 I-WP 型支架具有良好的力学性能,符合修复人体骨组织的要求,可为人工骨小梁支架的设计提供新的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
生物医学工程学杂志
生物医学工程学杂志 Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
4868
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