1827-LB: A Multilevel, mHealth-Based Culturally Tailored Diabetes Prevention Program for Chinese Immigrants—Preliminary Results from the INCLUDE Study

IF 6.2 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes Pub Date : 2024-06-21 DOI:10.2337/db24-1827-lb

NELSON LIN, YUN SHI, STELLA S. YI, MARY ANN SEVICK, HUILIN LI, JEANNETTE BEASLEY, YULIN JIANG, IRIS H. ONG, YUJIE BAI, XIMIN YANG, LIWEN SU, LU HU

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引用次数: 0

Abstract

Objective: Despite well-established evidence supporting the efficacy of the Diabetes Prevention Program (DPP), dissemination of the DPP to underserved communities is suboptimal. INCLUDE is an ADA-funded three year study to assess a multi-level mHealth intervention to provide a culturally tailored, language-concordant DPP and address food insecurity among Chinese immigrants. Here, we report feasibility data from Year 1 of the INCLUDE study. Methods: INCLUDE is a randomized clinical trial with Chinese American adults with BMI ≥ 23 at risk for diabetes with a planned sample size of 150 and intervention duration of 3 months. In Year 1, 75 patients were randomized to intervention (n=38) or control (n=37) groups. Intervention participants received 2-3 culturally adapted in-language DPP videos a week for 12 weeks, biweekly calls from trained bilingual (Mandarin Chinese) study staff, and culturally appropriate produce weekly for 10 weeks at a local farm. The primary aim of the study is to evaluate weight loss at 3 and 6 months. This report presents feasibility data for intervention participants. Results: Intervention participants (n=38, median age 48.5 [IQR 37.5-61.3]) were mostly female (84%), born outside the US (97%), and limited English proficient (82%). Participants reported an average video watch rate of 89% (SD 5.0%), a fresh produce pickup rate of 57% (SD 7.7%), a biweekly call completion rate of 81% (SD 15.5%). Overall retention rate was 95% at 3 months. Most (86%) participants agreed or strongly agreed that the program motivated weight loss, and all agreed or strongly agreed that the program increased confidence to prevent diabetes. Conclusion: Initial results demonstrate feasibility of a culturally adapted multi-level DPP intervention for underserved Chinese immigrants. Additional research with a longer duration and larger sample size is warranted to examine intervention effectiveness with adequate power. Disclosure N. Lin: None. Y. Shi: None. M. Sevick: None. H. Li: None. J. Beasley: None. Y. Jiang: None. I.H. Ong: None. Y. Bai: None. X. Yang: None. L. Su: None. L. Hu: None. Funding American Diabetes Association (7-22-ICTSN-08)

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1827-LB：基于移动医疗的多层次、针对中国移民文化的糖尿病预防计划--INCLUDE 研究的初步结果

目的：尽管已有大量证据支持糖尿病预防计划（DPP）的有效性，但该计划在服务不足社区的推广情况却不尽如人意。INCLUDE 是一项由美国糖尿病协会（ADA）资助的为期三年的研究，旨在评估一种多层次的移动医疗干预措施，以提供符合当地文化、语言一致的糖尿病预防计划，并解决中国移民的食物不安全问题。在此，我们报告 INCLUDE 研究第一年的可行性数据。研究方法INCLUDE 是一项随机临床试验，对象是体重指数（BMI）≥ 23 且有糖尿病风险的华裔成人，计划样本量为 150 人，干预时间为 3 个月。在第一年，75 名患者被随机分配到干预组（38 人）或对照组（37 人）。干预组参与者在 12 周内每周会收到 2-3 个经过文化调整的 DPP 语言视频，每两周会接到经过培训的双语（普通话）研究人员的电话，每周还会在当地农场收到 10 周的文化适宜农产品。研究的主要目的是评估 3 个月和 6 个月后的体重减轻情况。本报告介绍了干预参与者的可行性数据。研究结果干预参与者（38 人，中位年龄 48.5 [IQR：37.5-61.3]）大多为女性（84%），在美国以外出生（97%），英语水平有限（82%）。参与者的平均视频观看率为 89%（标准差为 5.0%），新鲜农产品采摘率为 57%（标准差为 7.7%），双周通话完成率为 81%（标准差为 15.5%）。3 个月后的总体保留率为 95%。大多数参与者（86%）同意或非常同意该计划能促进减肥，所有参与者都同意或非常同意该计划能增强预防糖尿病的信心。结论：初步研究结果表明，针对服务不足的中国移民开展文化适应性多层次 DPP 干预是可行的。有必要进行持续时间更长、样本量更大的其他研究，以充分检验干预的有效性。披露 N. Lin：无。Y. Shi: None.M. Sevick：无：M. Sevick: None.H. Li: None.J. 比斯利：无。Y. Jiang: None.I.H. Ong：无。Y. Bai：无。X. Yang：无。L. Su：无。L. Hu：无。资助机构美国糖尿病协会 (7-22-ICTSN-08)

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来源期刊

Diabetes 医学-内分泌学与代谢

CiteScore

12.50

自引率

2.60%

发文量

1968

审稿时长

1 months

期刊介绍： Diabetes is a scientific journal that publishes original research exploring the physiological and pathophysiological aspects of diabetes mellitus. We encourage submissions of manuscripts pertaining to laboratory, animal, or human research, covering a wide range of topics. Our primary focus is on investigative reports investigating various aspects such as the development and progression of diabetes, along with its associated complications. We also welcome studies delving into normal and pathological pancreatic islet function and intermediary metabolism, as well as exploring the mechanisms of drug and hormone action from a pharmacological perspective. Additionally, we encourage submissions that delve into the biochemical and molecular aspects of both normal and abnormal biological processes. However, it is important to note that we do not publish studies relating to diabetes education or the application of accepted therapeutic and diagnostic approaches to patients with diabetes mellitus. Our aim is to provide a platform for research that contributes to advancing our understanding of the underlying mechanisms and processes of diabetes.

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